Phenotype Images associated with this Gene

About Help FAQ

Phenotype Images associated with this Gene

Symbol
Name
ID

Wnt5a
wingless-type MMTV integration site family, member 5A
MGI:98958

Click on thumbnail to view full size image with links to phenotype annotations.
Click on allele symbol for full phenotype details.

	Caption: Primordial germ cell depletion in Ror2^Y324C/Ror2^Y324C and Wnt5a^tm1Amc/Wnt5a^tm1Amc mice (details) Represented Alleles: Ror2^Y324C, receptor tyrosine kinase-like orphan receptor 2; Tyr324Cys Wnt5a^tm1Amc, wingless-type MMTV integration site family, member 5A; targeted mutation 1, Andrew P McMahon Copyright: This image is from Laird DJ, PLoS Genet 2011 Dec;7(12):e1002428, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:179805
	Caption: Mutant 3077-006-2 (E15.5) exhibits parallel outflow tracts, pulmonary stenosis, and small left atrium later diagnosed as double outlet right ventricle (DORV), hypoplastic pulmonary artery, and hypoplastic left atrium by ECM histopathology. (details) Represented Alleles: b2b3077Clo, Mutant line 3077 Cecilia Lo; Bench to Bassinet Program (B2B/CVDC), mutation 3077 Cecilia Lo Wnt5a^b2b3077.1Clo, wingless-type MMTV integration site family, member 5A; Bench to Bassinet Program (B2B/CVDC), mutation 3077, subline 1 Cecilia Lo Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
	Caption: EFIC Summary (details) Represented Alleles: b2b3077Clo, Mutant line 3077 Cecilia Lo; Bench to Bassinet Program (B2B/CVDC), mutation 3077 Cecilia Lo Wnt5a^b2b3077.1Clo, wingless-type MMTV integration site family, member 5A; Bench to Bassinet Program (B2B/CVDC), mutation 3077, subline 1 Cecilia Lo Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
	Caption: Serial 2D ECM image stack of 3077-006-2 (E15.5) in the coronal plane reveals double outlet right ventricle (DORV), atrioventricular septal defect (AVSD), common atrium, hypoplastic pulmonary artery (PA), hypoplastic left atrium, and ventricular myocardial non-compaction. Click thumbnail to play movie. (details) Represented Alleles: b2b3077Clo, Mutant line 3077 Cecilia Lo; Bench to Bassinet Program (B2B/CVDC), mutation 3077 Cecilia Lo Wnt5a^b2b3077.1Clo, wingless-type MMTV integration site family, member 5A; Bench to Bassinet Program (B2B/CVDC), mutation 3077, subline 1 Cecilia Lo Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
	Caption: Color flow spectral Doppler imaging of mutant 3077-006-2 (E15.5) in the sagittal view shows only aorta overriding over septum, suggesting double outlet right ventricle (DORV) with pulmonary stenosis (PS) or pulmonary atresia. (details) Represented Alleles: b2b3077Clo, Mutant line 3077 Cecilia Lo; Bench to Bassinet Program (B2B/CVDC), mutation 3077 Cecilia Lo Wnt5a^b2b3077.1Clo, wingless-type MMTV integration site family, member 5A; Bench to Bassinet Program (B2B/CVDC), mutation 3077, subline 1 Cecilia Lo Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
	Caption: Mutant 3077-006-2 (E15.5) presents with hydrops, petechiae, short snout, micrognathia, short limbs, syndactyly, clubbed feet, and short tail. (details) Represented Alleles: b2b3077Clo, Mutant line 3077 Cecilia Lo; Bench to Bassinet Program (B2B/CVDC), mutation 3077 Cecilia Lo Wnt5a^b2b3077.1Clo, wingless-type MMTV integration site family, member 5A; Bench to Bassinet Program (B2B/CVDC), mutation 3077, subline 1 Cecilia Lo Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
	Caption: Mutant 3077-006-2 (E15.5) shows a cleft lip. (details) Represented Alleles: b2b3077Clo, Mutant line 3077 Cecilia Lo; Bench to Bassinet Program (B2B/CVDC), mutation 3077 Cecilia Lo Wnt5a^b2b3077.1Clo, wingless-type MMTV integration site family, member 5A; Bench to Bassinet Program (B2B/CVDC), mutation 3077, subline 1 Cecilia Lo Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
	Caption: Mutant 3077-006-2 (E15.5) presents with a cleft palate. (details) Represented Alleles: b2b3077Clo, Mutant line 3077 Cecilia Lo; Bench to Bassinet Program (B2B/CVDC), mutation 3077 Cecilia Lo Wnt5a^b2b3077.1Clo, wingless-type MMTV integration site family, member 5A; Bench to Bassinet Program (B2B/CVDC), mutation 3077, subline 1 Cecilia Lo Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
	Caption: Mutant 3077-006-2 (E15.5) exhibits a short gut. (details) Represented Alleles: b2b3077Clo, Mutant line 3077 Cecilia Lo; Bench to Bassinet Program (B2B/CVDC), mutation 3077 Cecilia Lo Wnt5a^b2b3077.1Clo, wingless-type MMTV integration site family, member 5A; Bench to Bassinet Program (B2B/CVDC), mutation 3077, subline 1 Cecilia Lo Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
	Caption: Mutant 3077-006-2 (E15.5) has an abnormal placement of the gonads and abnormal kidneys, later confirmed as duplex kidney with some glomerular cysts by histology (details) Represented Alleles: b2b3077Clo, Mutant line 3077 Cecilia Lo; Bench to Bassinet Program (B2B/CVDC), mutation 3077 Cecilia Lo Wnt5a^b2b3077.1Clo, wingless-type MMTV integration site family, member 5A; Bench to Bassinet Program (B2B/CVDC), mutation 3077, subline 1 Cecilia Lo Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/23/2024 MGI 6.23