Phenotype Images associated with this Gene

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Phenotype Images associated with this Gene

Symbol
Name
ID

Pkd1
polycystin 1, transient receptor potential channel interacting
MGI:97603

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Click on allele symbol for full phenotype details.

	Caption: Kidney cysts in Pkd1^tm1.1Pcha/Pkd1^tm1.1Pcha mice (details) Represented Alleles: Pkd1^tm1.1Pcha, polycystin 1, transient receptor potential channel interacting; targeted mutation 1.1, Peter Harris Copyright: This image is from Hopp K, J Clin Invest 2012 Nov 1;122(11):4257-73 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:193544
	Caption: Polycystic kidney disease in Pkd1^tm1.1Pcha/Pkd1^tm1.1Pcha mice (details) Represented Alleles: Pkd1^tm1.1Pcha, polycystin 1, transient receptor potential channel interacting; targeted mutation 1.1, Peter Harris Copyright: This image is from Hopp K, J Clin Invest 2012 Nov 1;122(11):4257-73 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:193544
	Caption: Pkd1^tm1.1Pcha/Pkd1^tm1Shh mice develop in utero/early-onset autosomal dominant polycystic kidney disease (details) Represented Alleles: Pkd1^tm1.1Pcha, polycystin 1, transient receptor potential channel interacting; targeted mutation 1.1, Peter Harris Pkd1^tm1Shh, polycystin 1, transient receptor potential channel interacting; targeted mutation 1, Shigeo Horie Copyright: This image is from Hopp K, J Clin Invest 2012 Nov 1;122(11):4257-73 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:193544
	Caption: Pkd1^tm1.1Pcha/Pkd1^tm1Shh mice show early-onset and rapidly progressive cystic disease (details) Represented Alleles: Pkd1^tm1.1Pcha, polycystin 1, transient receptor potential channel interacting; targeted mutation 1.1, Peter Harris Pkd1^tm1Shh, polycystin 1, transient receptor potential channel interacting; targeted mutation 1, Shigeo Horie Copyright: This image is from Hopp K, J Clin Invest 2012 Nov 1;122(11):4257-73 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:193544
	Caption: Pkd1^tm1.1Pcha/Pkd1^tm1.1Pcha and Pkd1^tm1.1Pcha/Pkd1^tm1Shh mice show a switch in tubular cyst origin (from proximal tubule to collecting duct) corresponding to age (details) Represented Alleles: Pkd1^tm1.1Pcha, polycystin 1, transient receptor potential channel interacting; targeted mutation 1.1, Peter Harris Pkd1^tm1Shh, polycystin 1, transient receptor potential channel interacting; targeted mutation 1, Shigeo Horie Copyright: This image is from Hopp K, J Clin Invest 2012 Nov 1;122(11):4257-73 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:193544
	Caption: Primary cilia are elongated in Pkd1^tm1.1Pcha/Pkd1^tm1.1Pcha and Pkd1^tm1.1Pcha/Pkd1^tm1Shh collecting ducts (details) Represented Alleles: Pkd1^tm1.1Pcha, polycystin 1, transient receptor potential channel interacting; targeted mutation 1.1, Peter Harris Pkd1^tm1Shh, polycystin 1, transient receptor potential channel interacting; targeted mutation 1, Shigeo Horie Copyright: This image is from Hopp K, J Clin Invest 2012 Nov 1;122(11):4257-73 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:193544
	Caption: Illustration of polycystic kidney disease progression and variation in Pkd1^tm1.1Pcha/Pkd1^tm1.1Pcha mice (details) Represented Alleles: Pkd1^tm1.1Pcha, polycystin 1, transient receptor potential channel interacting; targeted mutation 1.1, Peter Harris Copyright: This image is from Hopp K, J Clin Invest 2012 Nov 1;122(11):4257-73 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:193544
	Caption: Cyst development during embryogenesis and the first postnatal month in Pkd1^tm1.1Pcha/Pkd1^tm1.1Pcha and Pkd1^tm1.1Pcha/Pkd1^tm1Shh animals (details) Represented Alleles: Pkd1^tm1.1Pcha, polycystin 1, transient receptor potential channel interacting; targeted mutation 1.1, Peter Harris Pkd1^tm1Shh, polycystin 1, transient receptor potential channel interacting; targeted mutation 1, Shigeo Horie Copyright: This image is from Hopp K, J Clin Invest 2012 Nov 1;122(11):4257-73 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:193544
	Caption: Illustration of kidney cyst disease variation in Pkd1^tm1.1Pcha/Pkd1^tm1Shh mice (details) Represented Alleles: Pkd1^tm1.1Pcha, polycystin 1, transient receptor potential channel interacting; targeted mutation 1.1, Peter Harris Pkd1^tm1Shh, polycystin 1, transient receptor potential channel interacting; targeted mutation 1, Shigeo Horie Copyright: This image is from Hopp K, J Clin Invest 2012 Nov 1;122(11):4257-73 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:193544
	Caption: Anosteopenia in Pkd1^tm1.1Pcha/Pkd1^tm1Shh mice characterized by a decrease in cortical and trabecular bone mass (details) Represented Alleles: Pkd1^tm1.1Pcha, polycystin 1, transient receptor potential channel interacting; targeted mutation 1.1, Peter Harris Pkd1^tm1Shh, polycystin 1, transient receptor potential channel interacting; targeted mutation 1, Shigeo Horie Copyright: This image is from Hopp K, J Clin Invest 2012 Nov 1;122(11):4257-73 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:193544

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