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Symbol Name ID |
Pdgfrb
platelet derived growth factor receptor, beta polypeptide MGI:97531 |
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Caption: Mutant (E15.5) displays hypoplastic thymus.
(details)
Represented Alleles:
Pdgfrbb2b2903Clo,
platelet derived growth factor receptor, beta polypeptide; Bench to Bassinet Program (B2B/CVDC), mutation 2903 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: Mutant (E15.5) presents with abnormal arrangement of the outflow tract, later diagnosed as Tetralogy of Fallot (TOF) with overriding aorta, and hypoplastic pulmonary seen by ECM histopathology.
(details)
Represented Alleles:
Pdgfrbb2b2903Clo,
platelet derived growth factor receptor, beta polypeptide; Bench to Bassinet Program (B2B/CVDC), mutation 2903 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: EFIC Summary
(details)
Represented Alleles:
Pdgfrbb2b2903Clo,
platelet derived growth factor receptor, beta polypeptide; Bench to Bassinet Program (B2B/CVDC), mutation 2903 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: Serial 2D ECM imaging in the coronal plane of mutant (E15.5) reveals Tetralogy of Fallot (TOF) with overriding aorta, atrioventricular septal defect (AVSD), and hypoplastic pulmonary artery (PA).
Click thumbnail to play movie. (details) Represented Alleles:
Pdgfrbb2b2903Clo,
platelet derived growth factor receptor, beta polypeptide; Bench to Bassinet Program (B2B/CVDC), mutation 2903 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: Mutant (E15.5) has petechiae, hydrops, and short forelimbs.
(details)
Represented Alleles:
Pdgfrbb2b2903Clo,
platelet derived growth factor receptor, beta polypeptide; Bench to Bassinet Program (B2B/CVDC), mutation 2903 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: Mutant (E15.5) presents with hypoplastic thymus.
(details)
Represented Alleles:
Pdgfrbb2b2903Clo,
platelet derived growth factor receptor, beta polypeptide; Bench to Bassinet Program (B2B/CVDC), mutation 2903 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: EFIC Summary
(details)
Represented Alleles:
Pdgfrbb2b2903Clo,
platelet derived growth factor receptor, beta polypeptide; Bench to Bassinet Program (B2B/CVDC), mutation 2903 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: Serial 2D ECM image stack in the coronal plane of mutant (E15.5) reveals double outlet right ventricle (DORV), atrioventricular septal defect (AVSD), muscular ventricular septal defect (mVSD), and hypoplastic pulmonary artery (PA).
Click thumbnail to play movie. (details) Represented Alleles:
Pdgfrbb2b2903Clo,
platelet derived growth factor receptor, beta polypeptide; Bench to Bassinet Program (B2B/CVDC), mutation 2903 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: Mutant (E15.5) exhibits hydrops, petechiae, short snout, and mircrognathia.
(details)
Represented Alleles:
Pdgfrbb2b2903Clo,
platelet derived growth factor receptor, beta polypeptide; Bench to Bassinet Program (B2B/CVDC), mutation 2903 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: Mutant (E15.5) has clinodactyly on the left hindlimb
(details)
Represented Alleles:
Pdgfrbb2b2903Clo,
platelet derived growth factor receptor, beta polypeptide; Bench to Bassinet Program (B2B/CVDC), mutation 2903 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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