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Phenotype Images associated with this Gene
Symbol
Name
ID
b2b2459Clo
Mutant line 2459
MGI:5560781


19 phenotype image(s) for b2b2459Clo alleles
Showing image(s) 1 to 10
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Click on allele symbol for full phenotype details.

Caption: Mutant 2459-006-1 (E16.5) exhibits malalignment of the great arteries, shown to be double outlet right ventricle (DORV) by EFIC imaging (details)
Represented Alleles:
b2b2459Clo, Mutant line 2459; Bench to Bassinet Program (B2B/CVDC), mutation 2459 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: EFIC Summary (details)
Represented Alleles:
b2b2459Clo, Mutant line 2459; Bench to Bassinet Program (B2B/CVDC), mutation 2459 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Serial 2D EFIC image stack in the coronal plane of 2459-006-1 (E16.5) shows DORV, AVSD, RV non-compaction, LV hypertrophy, and cushion-like valves
Click thumbnail to play movie. (details)
Represented Alleles:
b2b2459Clo, Mutant line 2459; Bench to Bassinet Program (B2B/CVDC), mutation 2459 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Mutant 2459-006-1 (E16.5) presents with hydrops and ptechiae (details)
Represented Alleles:
b2b2459Clo, Mutant line 2459; Bench to Bassinet Program (B2B/CVDC), mutation 2459 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Mutant 2459-006-1 (E16.5) shows kidneys that appear cystic and have hydronephrosis (details)
Represented Alleles:
b2b2459Clo, Mutant line 2459; Bench to Bassinet Program (B2B/CVDC), mutation 2459 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Mutant 2459-006-1 has moderately cystic kidneys (details)
Represented Alleles:
b2b2459Clo, Mutant line 2459; Bench to Bassinet Program (B2B/CVDC), mutation 2459 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Mutant 2459-003-2 (E14.5) shows cystic and dysplastic kidneys (details)
Represented Alleles:
b2b2459Clo, Mutant line 2459; Bench to Bassinet Program (B2B/CVDC), mutation 2459 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: EFIC Summary (details)
Represented Alleles:
b2b2459Clo, Mutant line 2459; Bench to Bassinet Program (B2B/CVDC), mutation 2459 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Serial 2D EFIC image stack in the coronal plane of 2459-003-2 (E14.5) shows DORV, subaortic VSD, and dysplastic aortic valve
Click thumbnail to play movie. (details)
Represented Alleles:
b2b2459Clo, Mutant line 2459; Bench to Bassinet Program (B2B/CVDC), mutation 2459 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Color flow spectral Doppler imaging of mutant 2459-003-1 (E14.5) in the sagittal view shows both great arteries originating from the RV predominantly with sub aortic VSD, indicating DORV.
Click thumbnail to play (details)
Represented Alleles:
b2b2459Clo, Mutant line 2459; Bench to Bassinet Program (B2B/CVDC), mutation 2459 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory