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Phenotype Images associated with this Gene
Symbol
Name
ID
b2b1879Clo
Mutant line 1879
MGI:5476165


25 phenotype image(s) for b2b1879Clo alleles
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Caption: Mutant 1879-002-NA shows abnormal placement of the outflow with malformed pulmonary trunk and is diagnosed with DORV by EFIC imaging (details)
Represented Alleles:
Adamts6b2b1879.1Clo, ADAM metallopeptidase with thrombospondin type 1 motif 6; Bench to Bassinet Program (B2B/CVDC), mutation 1879.1 Cecilia Lo
b2b1879Clo, Mutant line 1879; Bench to Bassinet Program (B2B/CVDC), mutation 1879 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: EFIC Summary (details)
Represented Alleles:
Adamts6b2b1879.1Clo, ADAM metallopeptidase with thrombospondin type 1 motif 6; Bench to Bassinet Program (B2B/CVDC), mutation 1879.1 Cecilia Lo
b2b1879Clo, Mutant line 1879; Bench to Bassinet Program (B2B/CVDC), mutation 1879 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Serial 2D EFIC image stack in the coronal plane of 1879-002-NA reveals DORV, subaortic VSD, and biventricular hypertrophy
Click thumbnail to play movie. (details)
Represented Alleles:
Adamts6b2b1879.1Clo, ADAM metallopeptidase with thrombospondin type 1 motif 6; Bench to Bassinet Program (B2B/CVDC), mutation 1879.1 Cecilia Lo
b2b1879Clo, Mutant line 1879; Bench to Bassinet Program (B2B/CVDC), mutation 1879 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Mutant 1879-002-NA has a short snout, micrognathia, domed-shaped head, short limbs, and abnormally attached hindlimbs (details)
Represented Alleles:
Adamts6b2b1879.1Clo, ADAM metallopeptidase with thrombospondin type 1 motif 6; Bench to Bassinet Program (B2B/CVDC), mutation 1879.1 Cecilia Lo
b2b1879Clo, Mutant line 1879; Bench to Bassinet Program (B2B/CVDC), mutation 1879 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Mutant 1879-002-NA has midline defect with unfused sternum (details)
Represented Alleles:
Adamts6b2b1879.1Clo, ADAM metallopeptidase with thrombospondin type 1 motif 6; Bench to Bassinet Program (B2B/CVDC), mutation 1879.1 Cecilia Lo
b2b1879Clo, Mutant line 1879; Bench to Bassinet Program (B2B/CVDC), mutation 1879 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Mutant 1879-002-1 (E16.5) exhibits abnormally attached hindlimbs (details)
Represented Alleles:
Adamts6b2b1879.1Clo, ADAM metallopeptidase with thrombospondin type 1 motif 6; Bench to Bassinet Program (B2B/CVDC), mutation 1879.1 Cecilia Lo
b2b1879Clo, Mutant line 1879; Bench to Bassinet Program (B2B/CVDC), mutation 1879 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Mutant 1879-002-1 (E16.5) exhibits a cleft palate (details)
Represented Alleles:
Adamts6b2b1879.1Clo, ADAM metallopeptidase with thrombospondin type 1 motif 6; Bench to Bassinet Program (B2B/CVDC), mutation 1879.1 Cecilia Lo
b2b1879Clo, Mutant line 1879; Bench to Bassinet Program (B2B/CVDC), mutation 1879 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Mutant 1879-002-1 (E16.5) presents with an unfused sternum (details)
Represented Alleles:
Adamts6b2b1879.1Clo, ADAM metallopeptidase with thrombospondin type 1 motif 6; Bench to Bassinet Program (B2B/CVDC), mutation 1879.1 Cecilia Lo
b2b1879Clo, Mutant line 1879; Bench to Bassinet Program (B2B/CVDC), mutation 1879 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: EFIC Summary (details)
Represented Alleles:
Adamts6b2b1879.1Clo, ADAM metallopeptidase with thrombospondin type 1 motif 6; Bench to Bassinet Program (B2B/CVDC), mutation 1879.1 Cecilia Lo
b2b1879Clo, Mutant line 1879; Bench to Bassinet Program (B2B/CVDC), mutation 1879 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Serial 2D EFIC image stack in the coronal plane of mutant 1879-002-1 (E16.5) reveals overriding aorta, PA hypoplasia, and biventricular hypertrophy
Click thumbnail to play movie. (details)
Represented Alleles:
Adamts6b2b1879.1Clo, ADAM metallopeptidase with thrombospondin type 1 motif 6; Bench to Bassinet Program (B2B/CVDC), mutation 1879.1 Cecilia Lo
b2b1879Clo, Mutant line 1879; Bench to Bassinet Program (B2B/CVDC), mutation 1879 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory