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Symbol Name ID |
b2b1963Clo
Mutant line 1963 MGI:5467352 |
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Caption: Mutant 1963-002-3 (E16.5) exhibits a hypoplastic transverse arch and hypoplastic LV.
(details)
Represented Alleles:
b2b1963Clo,
Mutant line 1963; Bench to Bassinet Program (B2B/CVDC), mutation 1963 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: EFIC summary
(details)
Represented Alleles:
b2b1963Clo,
Mutant line 1963; Bench to Bassinet Program (B2B/CVDC), mutation 1963 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: Serial 2D EFIC image stack in the coronal plane of 1963-002-3 (E16.5) reveals HLHS, hypoplastic left ventricle, small mitral valve, left ventricular outflow tract obstruction, hypoplastic transverse aortic arch. Note the stack that showed aorta arising from RV is an artifact. Please refer to ultrasound imaging (http://www.informatics.jax.org/image/MGI:5644802), which clearly indicated aorta arising from left ventricle.
Click thumbnail to play movie. (details) Represented Alleles:
b2b1963Clo,
Mutant line 1963; Bench to Bassinet Program (B2B/CVDC), mutation 1963 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: Color flow spectral Doppler imaging of mutant 1963-002 in the sagittal view shows Ao emerging from hypoplastic LV, also note left outflow tract obstruction.
Click thumbnail to play movie. (details) Represented Alleles:
b2b1963Clo,
Mutant line 1963; Bench to Bassinet Program (B2B/CVDC), mutation 1963 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: Color flow spectral Doppler imaging of mutant 1963-002 in the sagittal view shows Ao emerging from hypoplastic LV
(details)
Represented Alleles:
b2b1963Clo,
Mutant line 1963; Bench to Bassinet Program (B2B/CVDC), mutation 1963 Cecilia Lo
b2b1963Clo,
Mutant line 1963; Bench to Bassinet Program (B2B/CVDC), mutation 1963 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: Color flow spectral Doppler imaging of mutant 1963-002 in the coronal view shows small size of mitral valve, small LV, no flow was detected in transverse arch, indicating hypoplastic LV, possible hypoplastic arch.
(details)
Represented Alleles:
b2b1963Clo,
Mutant line 1963; Bench to Bassinet Program (B2B/CVDC), mutation 1963 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: Mutant 1963-002-3 (E16.5) has hypoplastic thymus
(details)
Represented Alleles:
b2b1963Clo,
Mutant line 1963; Bench to Bassinet Program (B2B/CVDC), mutation 1963 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: Mutant 1963-002-3 (E16.5) has microphthalmia, clefting of the mouth and cleft palate
(details)
Represented Alleles:
b2b1963Clo,
Mutant line 1963; Bench to Bassinet Program (B2B/CVDC), mutation 1963 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: Mutant 1963-002-1 (E16.5) shows a hypoplastic transverse arch and LV hypertrophy
(details)
Represented Alleles:
b2b1963Clo,
Mutant line 1963; Bench to Bassinet Program (B2B/CVDC), mutation 1963 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Caption: EFIC summary
(details)
Represented Alleles:
b2b1963Clo,
Mutant line 1963; Bench to Bassinet Program (B2B/CVDC), mutation 1963 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors.
J:175213
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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