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Phenotype Images associated with this Gene
Symbol
Name
ID 		b2b1432Clo
Mutant line 1432
MGI:5445348


13 phenotype image(s) for b2b1432Clo alleles
Showing image(s) 1 to 10 		Show   figures per page Next Last
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Click on allele symbol for full phenotype details.

Caption: Mutant 1432-005-LA displays slightly narrow aorta and hypoplastic left ventricle. (details)
Represented Alleles:
b2b1432Clo, Mutant line 1432; Bench to Bassinet Program (B2B/CVDC), mutation 1432 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: EFIC Summary (details)
Represented Alleles:
b2b1432Clo, Mutant line 1432; Bench to Bassinet Program (B2B/CVDC), mutation 1432 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Serial 2D EFIC image stack in the coronal plane of 1432-005-LA reveals Hypoplastic LV, critical aortic stenosis, small mitral valve (HLHS), trabeculation within the ventricular septum, dilated aortic root, thickend and dysplastic aortic valve, and dilated RV with non-compaction.
Click thumbnail to play movie. (details)
Represented Alleles:
b2b1432Clo, Mutant line 1432; Bench to Bassinet Program (B2B/CVDC), mutation 1432 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Serial 2D EFIC image stack in the transverse plane of 1432-005-LA reveals dysplastic aortic valves, small left ventricle/mitral valve/left atrium, and normal sized left coronary artery
Click thumbnail to play movie. (details)
Represented Alleles:
b2b1432Clo, Mutant line 1432; Bench to Bassinet Program (B2B/CVDC), mutation 1432 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Serial 2D MRI image stack in the coronal plane of 1432-005-LA reveals small left atrium and hypoplastic left ventricle
Click thumbnail to play movie. (details)
Represented Alleles:
b2b1432Clo, Mutant line 1432; Bench to Bassinet Program (B2B/CVDC), mutation 1432 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Color flow spectral Doppler imaging of mutant 1432-005-LA in the sagittal view shows much less blood flow through aortic valve, suggesting severe aortic stenosis (details)
Represented Alleles:
b2b1432Clo, Mutant line 1432; Bench to Bassinet Program (B2B/CVDC), mutation 1432 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Color flow spectral Doppler movie of mutant 1432-005-LA in the sagittal view shows much less blood flow through the aortic valve, suggesting severe aortic stenosis
Click thumbnail to play movie. (details)
Represented Alleles:
b2b1432Clo, Mutant line 1432; Bench to Bassinet Program (B2B/CVDC), mutation 1432 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Color flow spectral Doppler movie of mutant 1432-005-LA in the sagittal view shows alignment of two great arteries is normal, but there is reversal of aortic blood flow indicating severe aortic stenosis
Click thumbnail to play movie. (details)
Represented Alleles:
b2b1432Clo, Mutant line 1432; Bench to Bassinet Program (B2B/CVDC), mutation 1432 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Color flow spectral Doppler imaging of mutant 1432-005-LA in the sagittal view shows aortic reverse blood flow, indicating severe aortic stenosis (details)
Represented Alleles:
b2b1432Clo, Mutant line 1432; Bench to Bassinet Program (B2B/CVDC), mutation 1432 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Spectral Doppler imaging of mutant 1432-005-LA in the sagittal view shows very high velocity at the level of the aortic valve, suggesting severe aortic stenosis (details)
Represented Alleles:
b2b1432Clo, Mutant line 1432; Bench to Bassinet Program (B2B/CVDC), mutation 1432 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory