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Phenotype Images associated with this Gene
Symbol
Name
ID 		Sgpp1
sphingosine-1-phosphate phosphatase 1
MGI:2135760


3 phenotype image(s) for Sgpp1 alleles
Showing image(s) 1 to 3
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Click on allele symbol for full phenotype details.

Caption: Sgpp2tm1Rlp/Sgpp2tm1Rlp mice showed normal skin appearance similar to wild-type mice, in contrast to severe ichtyosis in Sgpp1tm1(KOMP)Vlcg/Sgpp1tm1(KOMP)Vlcg mice (details)
Represented Alleles:
Sgpp1tm1(KOMP)Vlcg, sphingosine-1-phosphate phosphatase 1; targeted mutation 1, Velocigene
Sgpp1tm1(KOMP)Vlcg, sphingosine-1-phosphate phosphatase 1; targeted mutation 1, Velocigene
Sgpp2tm1Rlp, sphingosine-1-phosphate phosphatase 2; targeted mutation 1, Richard L Proia
Copyright: This image is from Taguchi Y, J Biol Chem 2016 Jun 3;291(23):12029-38 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:235035
Caption: Sgpp1tm1(KOMP)Vlcg/Sgpp1tm1(KOMP)Vlcg pups exhibit focal desquamation and abnormal epidermal histology (details)
Represented Alleles:
Sgpp1tm1(KOMP)Vlcg, sphingosine-1-phosphate phosphatase 1; targeted mutation 1, Velocigene
Sgpp1tm1(KOMP)Vlcg, sphingosine-1-phosphate phosphatase 1; targeted mutation 1, Velocigene
Copyright: This image is from Allende ML, J Biol Chem 2013 Jun 21;288(25):18381-91 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:199597
Caption: Abnormal skin in surviving Sgpp1tm1(KOMP)Vlcg/Sgpp1tm1(KOMP)Vlcg adult mice (details)
Represented Alleles:
Sgpp1tm1(KOMP)Vlcg, sphingosine-1-phosphate phosphatase 1; targeted mutation 1, Velocigene
Sgpp1tm1(KOMP)Vlcg, sphingosine-1-phosphate phosphatase 1; targeted mutation 1, Velocigene
Copyright: This image is from Allende ML, J Biol Chem 2013 Jun 21;288(25):18381-91 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:199597
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory