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Phenotype Images associated with this Gene
Symbol
Name
ID 		Cplane2
ciliogenesis and planar polarity effector 2
MGI:1923416


21 phenotype image(s) for Cplane2 alleles
Showing image(s) 1 to 10 		Show   figures per page Next Last
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Caption: Mutant (E14.5) shows persistent truncus arteriosus (PTA), and dual inferior vena cava (IVC), which was confirmed by ECM imaging. (details)
Represented Alleles:
Cplane2b2b2804Clo, ciliogenesis and planar polarity effector 2; Bench to Bassinet Program (B2B/CVDC), mutation 2804 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Mutant 2827-004-1 (E16.5) exhibits heterotaxy with dextrocardia, PTA, and hypoplastic lungs (details)
Represented Alleles:
Cplane2b2b2827Clo, ciliogenesis and planar polarity effector 2; Bench to Bassinet Program (B2B/CVDC), mutation 2827 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: EFIC Summary (details)
Represented Alleles:
Cplane2b2b2827Clo, ciliogenesis and planar polarity effector 2; Bench to Bassinet Program (B2B/CVDC), mutation 2827 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: EFIC Summary (details)
Represented Alleles:
Cplane2b2b2804Clo, ciliogenesis and planar polarity effector 2; Bench to Bassinet Program (B2B/CVDC), mutation 2804 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Serial 2D EFIC stack of 2827-004-1 (E16.5) in the coronal plane reveals dextrocardia {A,A(D),A}, superior-inferior ventricles, juxtaposition of atria, AVSD, common atrium, RAA, pulmonary atresia, tracheoesophageal fistula, and no major pulmonary arteries identified
Click thumbnail to play movie. (details)
Represented Alleles:
Cplane2b2b2827Clo, ciliogenesis and planar polarity effector 2; Bench to Bassinet Program (B2B/CVDC), mutation 2827 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Serial 2D EFIC image stack in the coronal plane of mutant (E14.5) reveals PTA {A,D,D(A)}, atrioventricular septa defects (AVSD), common atrium, dual inferior vena cava (IVC), absent pulmonary artery (PA) branch, and hypoplastic lungs with trachea and bronchi not identified.
Click thumbnail to play movie. (details)
Represented Alleles:
Cplane2b2b2804Clo, ciliogenesis and planar polarity effector 2; Bench to Bassinet Program (B2B/CVDC), mutation 2804 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Mutant 2827-004-1 (E16.5) exhibits preaxial and central polydactyly on all limbs, microphthalmia, hydrops, and micrognathia (details)
Represented Alleles:
Cplane2b2b2827Clo, ciliogenesis and planar polarity effector 2; Bench to Bassinet Program (B2B/CVDC), mutation 2827 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Color flow spectral Doppler imaging of mutant (E14.5) in the sagittal view shows one great artery originating from heart with regurgitation, suggesting PTA.
Click thumbnail to play movie. (details)
Represented Alleles:
Cplane2b2b2804Clo, ciliogenesis and planar polarity effector 2; Bench to Bassinet Program (B2B/CVDC), mutation 2804 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Mutant (E14.5) exhibits preaxial digit duplication and central polydactyly, hydrops, micrognathia, and anophthalmia. (details)
Represented Alleles:
Cplane2b2b2804Clo, ciliogenesis and planar polarity effector 2; Bench to Bassinet Program (B2B/CVDC), mutation 2804 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Mutant 2827-004-1 (E16.5) shows a cleft lip (details)
Represented Alleles:
Cplane2b2b2827Clo, ciliogenesis and planar polarity effector 2; Bench to Bassinet Program (B2B/CVDC), mutation 2827 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory