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Phenotype Images associated with this Gene
Symbol
Name
ID
Adamts6
ADAM metallopeptidase with thrombospondin type 1 motif 6
MGI:1347348


139 phenotype image(s) for Adamts6 alleles
Showing image(s) 81 to 90
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Click on allele symbol for full phenotype details.

Caption: Color flow Doppler imaging in the transverse view of mutant 2407-003-4 (E16.5) shows a VSD (details)
Represented Alleles:
Adamts6b2b2407Clo, ADAM metallopeptidase with thrombospondin type 1 motif 6; Bench to Bassinet Program (B2B/CVDC), mutation 2407 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Serial 2D EFIC image stack in the coronal plane of 2405-003-6 (E15.5) shows overriding aorta, AVSD, and biventricular hypertrophy
Click thumbnail to play movie. (details)
Represented Alleles:
Adamts6b2b2405Clo, ADAM metallopeptidase with thrombospondin type 1 motif 6; Bench to Bassinet Program (B2B/CVDC), mutation 2405 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Serial 2D EFIC image stack in the coronal plane of mutant 2744-002-2 (E15.5) shows DORV, AVSD, and thickened AV valves
Click thumbnail to play movie. (details)
Represented Alleles:
Adamts6b2b2744Clo, ADAM metallopeptidase with thrombospondin type 1 motif 6; Bench to Bassinet Program (B2B/CVDC), mutation 2744 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Color flow spectral Doppler imaging of mutant 1879-002-1 (E16.5) in the saggital view shows aorta overriding on the ventricular septum, VSD, blood flow only can be detected in aorta. Notice a small vessel beside aorta, but no blood flow inside. This together suggests PA, VSD
Click thumbnail to play movie. (details)
Represented Alleles:
Adamts6b2b1879.1Clo, ADAM metallopeptidase with thrombospondin type 1 motif 6; Bench to Bassinet Program (B2B/CVDC), mutation 1879.1 Cecilia Lo
b2b1879Clo, Mutant line 1879; Bench to Bassinet Program (B2B/CVDC), mutation 1879 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Serial 2D EFIC image stack of 2029-003-NB in the coronal view exhibits overriding aorta, perimembranous VSD, dilated pulmonary artery (PA), thick semilunar valves and biventricular hypertrophy
Click thumbnail to play movie. (details)
Represented Alleles:
Adamts6b2b2029Clo, ADAM metallopeptidase with thrombospondin type 1 motif 6; Bench to Bassinet Program (B2B/CVDC), mutation 2029 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Serial 2D EFIC image stack in of 2228-004-1 (E14.5) in the the coronal plane shows DORV and subaortic VSD
Click thumbnail to play movie. (details)
Represented Alleles:
Adamts6b2b2228Clo, ADAM metallopeptidase with thrombospondin type 1 motif 6; Bench to Bassinet Program (B2B/CVDC), mutation 2228 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Serial 2D EFIC image stack in the coronal plane of 2182-003-2 (E15.5) exhibits DORV, AVSD, and biventricular hypertrophy
Click thumbnail to play movie. (details)
Represented Alleles:
Adamts6b2b2182Clo, ADAM metallopeptidase with thrombospondin type 1 motif 6; Bench to Bassinet Program (B2B/CVDC), mutation 2182 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Mutant 2407-003-3 (E16.5) exhibits a short snout and abnormally attached hindlimbs (details)
Represented Alleles:
Adamts6b2b2407Clo, ADAM metallopeptidase with thrombospondin type 1 motif 6; Bench to Bassinet Program (B2B/CVDC), mutation 2407 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Color flow spectral Doppler imaging of mutant fetus 2187-004-1 (E16.5) in the transverse view shows aliasing with increased blood flow through inflow tracts, suggesting atrioventricular valve stenosis (details)
Represented Alleles:
Adamts6b2b2187.1Clo, ADAM metallopeptidase with thrombospondin type 1 motif 6; Bench to Bassinet Program (B2B/CVDC), mutation 2187, subline 1, Cecilia Lo
b2b2187Clo, Mutant line 2187; Bench to Bassinet Program (B2B/CVDC), mutation 2187 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Snapshot of video of Color flow spectral Doppler imaging for mutant 1879-002-1 (E16.5) in the sagittal view shows aorta overriding on the ventricular septum, VSD, blood flow only can be detected in aorta. Notice a small vessel beside aorta, but no blood flow inside. This together suggests PA, VSD (details)
Represented Alleles:
Adamts6b2b1879.1Clo, ADAM metallopeptidase with thrombospondin type 1 motif 6; Bench to Bassinet Program (B2B/CVDC), mutation 1879.1 Cecilia Lo
b2b1879Clo, Mutant line 1879; Bench to Bassinet Program (B2B/CVDC), mutation 1879 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory