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Phenotype Images associated with this Gene
Symbol
Name
ID 		Dvl3
dishevelled segment polarity protein 3
MGI:108100


16 phenotype image(s) for Dvl3 alleles
Showing image(s) 1 to 10 		Show   figures per page Next Last
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Click on allele symbol for full phenotype details.

Caption: Mutant (E14.5) presents with malaligned outflow tracts, later diagnosed as double outlet right ventricle (DORV) by ECM histopathology. (details)
Represented Alleles:
Dvl3b2b2866Clo, dishevelled segment polarity protein 3; Bench to Bassinet Program (B2B/CVDC), mutation 2866 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: EFIC Summary (details)
Represented Alleles:
Dvl3b2b2866Clo, dishevelled segment polarity protein 3; Bench to Bassinet Program (B2B/CVDC), mutation 2866 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Serial 2D ECM image stack in the coronal plane of mutant (E14.5) reveals double outlet right ventricle (DORV), subaortic VSD, and cushion-like semilunar valves
Click thumbnail to play movie. (details)
Represented Alleles:
Dvl3b2b2866Clo, dishevelled segment polarity protein 3; Bench to Bassinet Program (B2B/CVDC), mutation 2866 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Mutant (E14.5) shows a hypoplastic thymus. (details)
Represented Alleles:
Dvl3b2b2866Clo, dishevelled segment polarity protein 3; Bench to Bassinet Program (B2B/CVDC), mutation 2866 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Mutant (E14.5) presents with a short snout and micrognathia. (details)
Represented Alleles:
Dvl3b2b2866Clo, dishevelled segment polarity protein 3; Bench to Bassinet Program (B2B/CVDC), mutation 2866 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Mutant (E14.5) presents with malpositioned pulmonary artery (PA), later diagnosed as double outlet right ventricle by ECM histopathology. (details)
Represented Alleles:
Dvl3b2b2866Clo, dishevelled segment polarity protein 3; Bench to Bassinet Program (B2B/CVDC), mutation 2866 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Color flow spectral Doppler imaging of mutant (E14.5) in the sagittal view shows two great arteries originating from the right ventricle (RV) primarily with pulmonary artery (PA) insufficiency, a shunt between the left and right ventricle beneath the aorta, suggesting double outlet right ventricle (DORV).
Click thumbnail to play movie. (details)
Represented Alleles:
Dvl3b2b2866Clo, dishevelled segment polarity protein 3; Bench to Bassinet Program (B2B/CVDC), mutation 2866 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: EFIC Summary (details)
Represented Alleles:
Dvl3b2b2866Clo, dishevelled segment polarity protein 3; Bench to Bassinet Program (B2B/CVDC), mutation 2866 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Serial 2D ECM image stack in the coronal plane of mutant (E14.5) reveals double outlet right ventricle (DORV) and subaortic VSD.
Click thumbnail to play movie. (details)
Represented Alleles:
Dvl3b2b2866Clo, dishevelled segment polarity protein 3; Bench to Bassinet Program (B2B/CVDC), mutation 2866 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Mutant (E14.5) presents with a short snout and micrognathia. (details)
Represented Alleles:
Dvl3b2b2866Clo, dishevelled segment polarity protein 3; Bench to Bassinet Program (B2B/CVDC), mutation 2866 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/30/2024
MGI 6.23 		The Jackson Laboratory