 | Mutant (E14.5) shows persistent truncus arteriosus (PTA), and dual inferior vena cava (IVC), which was confirmed by ECM imaging. | Cplane2b2b2804Clo/Cplane2b2b2804Clo | C57BL/6J-Cplane2b2b2804Clo |
 | EFIC Summary | Cplane2b2b2804Clo/Cplane2b2b2804Clo | C57BL/6J-Cplane2b2b2804Clo |
 | Serial 2D EFIC image stack in the coronal plane of mutant (E14.5) reveals PTA {A,D,D(A)}, atrioventricular septa defects (AVSD), common atrium, dual inferior vena cava (IVC), absent pulmonary artery (PA) branch, and hypoplastic lungs with trachea and bronchi not identified.
Click thumbnail to play movie. | Cplane2b2b2804Clo/Cplane2b2b2804Clo | C57BL/6J-Cplane2b2b2804Clo |
 | Color flow spectral Doppler imaging of mutant (E14.5) in the sagittal view shows one great artery originating from heart with regurgitation, suggesting PTA.
Click thumbnail to play movie. | Cplane2b2b2804Clo/Cplane2b2b2804Clo | C57BL/6J-Cplane2b2b2804Clo |
 | Mutant (E14.5) exhibits preaxial digit duplication and central polydactyly, hydrops, micrognathia, and anophthalmia. | Cplane2b2b2804Clo/Cplane2b2b2804Clo | C57BL/6J-Cplane2b2b2804Clo |
 | EFIC Summary | Cplane2b2b2804Clo/Cplane2b2b2804Clo | C57BL/6J-Cplane2b2b2804Clo |
 | Serial 2D ECM image stack in the coronal plane of mutant (E14.5) reveals developmental arrest, persistent truncus arteriosus (PTA-Type 1), and cushion-like atrioventricular valve.
Click thumbnail to play movie. | Cplane2b2b2804Clo/Cplane2b2b2804Clo | C57BL/6J-Cplane2b2b2804Clo |
 | Mutant (E14.5) shows persistent truncus arteriosus (PTA), which was diagnosed by ECM imaging as PTA-type I. | | |
 | Mutant (E14.5) shows polydactyly, micrognathia, short snout, and microphthalmia | Cplane2b2b2804Clo/Cplane2b2b2804Clo | C57BL/6J-Cplane2b2b2804Clo |
Analysis Tools