Phenotype Images associated with this Allele - MGI

About Help FAQ

Phenotype Images associated with this Allele

Nomenclature

Symbol:	Cplane2^b2b2827Clo
Name:	ciliogenesis and planar polarity effector 2; Bench to Bassinet Program (B2B/CVDC), mutation 2827 Cecilia Lo
MGI ID:	MGI:5560911

Images for
Allele

Click images for details

Image	Caption	Genotypes involving this allele
Image	Caption	Allelic Composition	Genetic Background
	Mutant 2827-004-1 (E16.5) exhibits heterotaxy with dextrocardia, PTA, and hypoplastic lungs	Cplane2^b2b2827Clo/Cplane2^b2b2827Clo	C57BL/6J-Cplane2^b2b2827Clo
	EFIC Summary	Cplane2^b2b2827Clo/Cplane2^b2b2827Clo	C57BL/6J-Cplane2^b2b2827Clo
	Serial 2D EFIC stack of 2827-004-1 (E16.5) in the coronal plane reveals dextrocardia {A,A(D),A}, superior-inferior ventricles, juxtaposition of atria, AVSD, common atrium, RAA, pulmonary atresia, tracheoesophageal fistula, and no major pulmonary arteries identified Click thumbnail to play movie.	Cplane2^b2b2827Clo/Cplane2^b2b2827Clo	C57BL/6J-Cplane2^b2b2827Clo
	Mutant 2827-004-1 (E16.5) exhibits preaxial and central polydactyly on all limbs, microphthalmia, hydrops, and micrognathia	Cplane2^b2b2827Clo/Cplane2^b2b2827Clo	C57BL/6J-Cplane2^b2b2827Clo
	Mutant 2827-004-1 (E16.5) shows a cleft lip	Cplane2^b2b2827Clo/Cplane2^b2b2827Clo	C57BL/6J-Cplane2^b2b2827Clo
	Mutant 2827-004-1 (E16.5) shows a hypoplastic thymus	Cplane2^b2b2827Clo/Cplane2^b2b2827Clo	C57BL/6J-Cplane2^b2b2827Clo
	Mutant 2827-004-1 (E16.5) exhibits heterotaxy with dextrocardia and levogastria	Cplane2^b2b2827Clo/Cplane2^b2b2827Clo	C57BL/6J-Cplane2^b2b2827Clo
	Mutant 2827-004-2 (E16.5) has PTA and hypoplastic lungs as confirmed by EFIC imaging	Cplane2^b2b2827Clo/Cplane2^b2b2827Clo	C57BL/6J-Cplane2^b2b2827Clo
	EFIC Summary	Cplane2^b2b2827Clo/Cplane2^b2b2827Clo	C57BL/6J-Cplane2^b2b2827Clo
	Serial 2D EFIC image stack of 2827-004-2 (E16.5) in the coronal plane reveals PTA {A,D,D(A)}, AVSD, common atrium, hypoplastic lungs connected to esophagus, trachea not identified, right IVC and left hepatic vein connected to atrium Click thumbnail to play movie.	Cplane2^b2b2827Clo/Cplane2^b2b2827Clo	C57BL/6J-Cplane2^b2b2827Clo
	Mutant 2827-004-2 (E16.5) is runted, has preaxial and central polydactyly on all limbs, cleft lip, and anophthalmia	Cplane2^b2b2827Clo/Cplane2^b2b2827Clo	C57BL/6J-Cplane2^b2b2827Clo
	Mutant 2827-004-2 (E16.5) presents with anophthalmia, micrognathia, and hydrops	Cplane2^b2b2827Clo/Cplane2^b2b2827Clo	C57BL/6J-Cplane2^b2b2827Clo

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/23/2024 MGI 6.23