Phenotype Images associated with this Allele - MGI

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Phenotype Images associated with this Allele

Nomenclature

Symbol:	Adamts6^b2b2744Clo
Name:	ADAM metallopeptidase with thrombospondin type 1 motif 6; Bench to Bassinet Program (B2B/CVDC), mutation 2744 Cecilia Lo
MGI ID:	MGI:5560500

Images for
Allele

Click images for details

Image	Caption	Genotypes involving this allele
Image	Caption	Allelic Composition	Genetic Background
	Mutant 2744-002-1 (E15.5) presents with hypoplastic PA, parallel outflow tracts, and thin ventricle walls which is diagnosed as DORV and ventricular non-compaction by EFIC imaging	Adamts6^b2b2744Clo/Adamts6^b2b2744Clo	C57BL/6J-Adamts6^b2b2744Clo
	EFIC Summary	Adamts6^b2b2744Clo/Adamts6^b2b2744Clo	C57BL/6J-Adamts6^b2b2744Clo
	Serial 2D EFIC image stack in the coronal plane of mutant 2744-002-1 (E15.5) shows DORV, AVSD, hypoplastic PA, and ventricular non-compaction Click thumbnail to play movie.	Adamts6^b2b2744Clo/Adamts6^b2b2744Clo	C57BL/6J-Adamts6^b2b2744Clo
	Mutant 2744-002-1 (e15.5) shows hydrops, abnormally attached hindlimbs, short snout, and micrognathia	Adamts6^b2b2744Clo/Adamts6^b2b2744Clo	C57BL/6J-Adamts6^b2b2744Clo
	Mutant 2744-002-1 (E15.5) presents with a cleft palate	Adamts6^b2b2744Clo/Adamts6^b2b2744Clo	C57BL/6J-Adamts6^b2b2744Clo
	Mutant 2744-002-1 (E15.5) shows a hypoplastic thymus	Adamts6^b2b2744Clo/Adamts6^b2b2744Clo	C57BL/6J-Adamts6^b2b2744Clo
	Mutant 2744-002-2 (E15.5) shows hydrops, abnormally attached hindlimbs, short snout, and micrognathia	Adamts6^b2b2744Clo/Adamts6^b2b2744Clo	C57BL/6J-Adamts6^b2b2744Clo
	Mutant 2744-002-2 (E15.5) exhibits a cleft palate	Adamts6^b2b2744Clo/Adamts6^b2b2744Clo	C57BL/6J-Adamts6^b2b2744Clo
	Mutant 2744-002-2 (E15.5) is developmentally delayed with abnormal placement of the great arteries and is diagnosed with DORV that was found by EFIC imaging	Adamts6^b2b2744Clo/Adamts6^b2b2744Clo	C57BL/6J-Adamts6^b2b2744Clo
	EFIC Summary	Adamts6^b2b2744Clo/Adamts6^b2b2744Clo	C57BL/6J-Adamts6^b2b2744Clo
	Serial 2D EFIC image stack in the coronal plane of mutant 2744-002-2 (E15.5) shows DORV, AVSD, and thickened AV valves Click thumbnail to play movie.	Adamts6^b2b2744Clo/Adamts6^b2b2744Clo	C57BL/6J-Adamts6^b2b2744Clo

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