About   Help   FAQ
Phenotype Images associated with this Allele
Nomenclature
Symbol: Adamts6b2b2405Clo
Name: ADAM metallopeptidase with thrombospondin type 1 motif 6; Bench to Bassinet Program (B2B/CVDC), mutation 2405 Cecilia Lo
MGI ID: MGI:5560144
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Mutant 2405-003-2 (E15.5) exhibits abnormal placement of the great arteries which is diagnosed as DORV by EFIC imagingAdamts6b2b2405Clo/Adamts6b2b2405CloC57BL/6J-Adamts6b2b2405Clo
EFIC SummaryAdamts6b2b2405Clo/Adamts6b2b2405CloC57BL/6J-Adamts6b2b2405Clo
Serial 2D EFIC image stack in the coronal plane of 2405-003-2 (E15.5) shows DORV and subaortic VSD
Click thumbnail to play movie.		Adamts6b2b2405Clo/Adamts6b2b2405CloC57BL/6J-Adamts6b2b2405Clo
Mutant 2405-003-2 (E15.5) presents with abnormally attached hindlimbs and hydropsAdamts6b2b2405Clo/Adamts6b2b2405CloC57BL/6J-Adamts6b2b2405Clo
Mutant 2405-003-2 (E15.5) has a hypoplastic thymusAdamts6b2b2405Clo/Adamts6b2b2405CloC57BL/6J-Adamts6b2b2405Clo
Mutant 2405-003-6 (E15.5) presents with a short snout, abnormally attached hindlimbs, and hydropsAdamts6b2b2405Clo/Adamts6b2b2405CloC57BL/6J-Adamts6b2b2405Clo
Mutant 2405-003-6 (E15.5) shows a hypoplastic thymusAdamts6b2b2405Clo/Adamts6b2b2405CloC57BL/6J-Adamts6b2b2405Clo
Mutant 2405-003-6 (E15.5) presents with a hypoplastic transverse arch and biventricular hypertrophy which was also seen by EFIC imagingAdamts6b2b2405Clo/Adamts6b2b2405CloC57BL/6J-Adamts6b2b2405Clo
EFIC SummaryAdamts6b2b2405Clo/Adamts6b2b2405CloC57BL/6J-Adamts6b2b2405Clo
Serial 2D EFIC image stack in the coronal plane of 2405-003-6 (E15.5) shows overriding aorta, AVSD, and biventricular hypertrophy
Click thumbnail to play movie.		Adamts6b2b2405Clo/Adamts6b2b2405CloC57BL/6J-Adamts6b2b2405Clo
Mutant 2405-005-NA has abnormally attached hindlimbs, a short snout, and micrognathiaAdamts6b2b2405Clo/Adamts6b2b2405CloC57BL/6J-Adamts6b2b2405Clo
Mutant 2405-005-NA exhibits an unfused sternumAdamts6b2b2405Clo/Adamts6b2b2405CloC57BL/6J-Adamts6b2b2405Clo
Mutant 2405-005-NA presents with a hypoplastic thymusAdamts6b2b2405Clo/Adamts6b2b2405CloC57BL/6J-Adamts6b2b2405Clo
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory