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Phenotype Images associated with this Allele
Nomenclature
Symbol: Csnk1a1tm1.1Ybn
Name: casein kinase 1, alpha 1; targeted mutation 1.1, Yinon Ben-Neriah
MGI ID: MGI:5543667
Synonyms: Csnk1a1fl
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Csnk1a1tm1.1Ybn/Csnk1a1tm1.1Ybn Tg(KRT14-cre/ERT)20Efu/0 mice show skin hyperpigmentation of ears, paws, mouth, and trunk after tamoxifen treatmentCsnk1a1tm1.1Ybn/Csnk1a1tm1.1Ybn
Tg(KRT14-cre/ERT)20Efu/0		involves: 129S1/Sv * 129X1/SvJ * CD-1
Immunohistochemistry of paw skin in tamoxifen-treated Csnk1a1tm1.1Ybn/Csnk1a1tm1.1Ybn Tg(KRT14-cre/ERT)20Efu/0 miceCsnk1a1tm1.1Ybn/Csnk1a1tm1.1Ybn
Tg(KRT14-cre/ERT)20Efu/0		involves: 129S1/Sv * 129X1/SvJ * CD-1
Topical treatment with tamoxifen for 14 days induces skin hyperpigmentation on the ear in Csnk1a1tm1.1Ybn/Csnk1a1tm1.1Ybn Tg(KRT14-cre/ERT)20Efu/0 miceCsnk1a1tm1.1Ybn/Csnk1a1tm1.1Ybn
Tg(KRT14-cre/ERT)20Efu/0		involves: 129S1/Sv * 129X1/SvJ * CD-1
Skin hyperpigmentation in Csnk1a1tm1.1Ybn/Csnk1a1tm1.1Ybn Tg(KRT14-cre/ERT)20Efu/0 mice but not in Csnk1a1tm1.1Ybn/Csnk1a1tm1.1Ybn Trp53tm1Brn/Trp53tm1Brn Tg(KRT14-cre/ERT)20Efu/0 miceCsnk1a1tm1.1Ybn/Csnk1a1tm1.1Ybn
Tg(KRT14-cre/ERT)20Efu/0		involves: 129S1/Sv * 129X1/SvJ * CD-1
Csnk1a1tm1.1Ybn/Csnk1a1tm1.1Ybn
Trp53tm1Brn/Trp53tm1Brn
Tg(KRT14-cre/ERT)20Efu/0		involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * CD-1
Intradermal injection of an anti-Kit antibody (ACK2) decreases the number of melanocytes in the epidermis of Csnk1a1tm1.1Ybn/Csnk1a1tm1.1Ybn Tg(KRT14-cre/ERT)20Efu/0 (SKO) miceCsnk1a1tm1.1Ybn/Csnk1a1tm1.1Ybn
Tg(KRT14-cre/ERT)20Efu/0		involves: 129S1/Sv * 129X1/SvJ * CD-1
Sunburn damage (swelling of the tail) after UVB exposure is not seen in eumelanized tails of Csnk1a1tm1.1Ybn/Csnk1a1tm1.1Ybn Tg(KRT14-cre/ERT)20Efu miceCsnk1a1tm1.1Ybn/Csnk1a1tm1.1Ybn
Tg(KRT14-cre/ERT)20Efu/0		involves: 129S1/Sv * 129X1/SvJ * CD-1
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory