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Phenotype Images associated with this Allele
Nomenclature
Symbol: Kif7b2b2254Clo
Name: kinesin family member 7; Bench to Bassinet Program (B2B/CVDC) mutation 2254, Cecilia Lo
MGI ID: MGI:5498230
Synonyms: Rocco
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Mutant 2254-002-1 (E14.5) has DORV, right aortic arch (RAA), and hypoplastic PAKif7b2b2254Clo/Kif7b2b2254CloC57BL/6J-Kif7b2b2254Clo
EFIC SummaryKif7b2b2254Clo/Kif7b2b2254CloC57BL/6J-Kif7b2b2254Clo
Serial 2D EFIC image stack in the coronal plane of 2254-002-1 (E14.5) exhibits DORV, AVSD, RAA, incomplete vascular ring, and hypoplastic PA
Click thumbnail to play movie.		Kif7b2b2254Clo/Kif7b2b2254CloC57BL/6J-Kif7b2b2254Clo
Mutant 2254-002-2 (E14.5) exhibits a hypoplastic pulmonary trunk and malpositioning of the outflow tracts which was diagnosed as overriding aorta by EFIC imagingKif7b2b2254Clo/Kif7b2b2254CloC57BL/6J-Kif7b2b2254Clo
EFIC SummaryKif7b2b2254Clo/Kif7b2b2254CloC57BL/6J-Kif7b2b2254Clo
Serial 2D EFIC image stack in the coronal plane of 2254-002-2 (14.5) shows overriding aorta, pmVSD, and hypoplastic PA
Click thumbnail to play movie.		Kif7b2b2254Clo/Kif7b2b2254CloC57BL/6J-Kif7b2b2254Clo
Mutant 2254-002-4 (E14.5) has hypoplastic thymus glands that have not descendedKif7b2b2254Clo/Kif7b2b2254CloC57BL/6J-Kif7b2b2254Clo
Mutant 2254-002-4 (E14.5) has pulmonary stenosisKif7b2b2254Clo/Kif7b2b2254CloC57BL/6J-Kif7b2b2254Clo
EFIC SummaryKif7b2b2254Clo/Kif7b2b2254CloC57BL/6J-Kif7b2b2254Clo
Serial 2D EFIC image stack in the coronal plane of 2254-002-4 (E14.5) shows AVSD and hypoplastic PA
Click thumbnail to play movie.		Kif7b2b2254Clo/Kif7b2b2254CloC57BL/6J-Kif7b2b2254Clo
Mutant 2254-002-1 (E14.5) has excencephaly, facial cleft, polydactylyKif7b2b2254Clo/Kif7b2b2254CloC57BL/6J-Kif7b2b2254Clo
Mutant 2254-002-2 (E14.5) has hydrops, anopthalmia, and polydactylyKif7b2b2254Clo/Kif7b2b2254CloC57BL/6J-Kif7b2b2254Clo
Mutant 2254-002-3 (E14.5) has anopthalmia, possible hydrocephaly, and polydactyly with 6-8 digitsKif7b2b2254Clo/Kif7b2b2254CloC57BL/6J-Kif7b2b2254Clo
Mutant 2254-002-4 (E14.5) has hydrops, micropthalmia, and polydactylyKif7b2b2254Clo/Kif7b2b2254CloC57BL/6J-Kif7b2b2254Clo
Mutant 2254-002-5 (E14..5) has anopthalmia and polydactyly with preaxial digit duplication and central polydactylyKif7b2b2254Clo/Kif7b2b2254CloC57BL/6J-Kif7b2b2254Clo
Mutant 2254-002-1 (E14.5) exhibits preaxial digit duplication and syndactylyKif7b2b2254Clo/Kif7b2b2254CloC57BL/6J-Kif7b2b2254Clo
Mutant 2254-002-2 (E14.5) exhibits preaxial digit duplication with syndactylyKif7b2b2254Clo/Kif7b2b2254CloC57BL/6J-Kif7b2b2254Clo
Mutant 2254-002-4 (E14.5) exhibits microphthalmia and preaxial digit duplication and polydactyly/syndactylyKif7b2b2254Clo/Kif7b2b2254CloC57BL/6J-Kif7b2b2254Clo
Mutant 2254-002-2 (E14.5) has cleft palateKif7b2b2254Clo/Kif7b2b2254CloC57BL/6J-Kif7b2b2254Clo
Mutant 2254-002-5 (E14.5) shows abnormal development of the gonadsKif7b2b2254Clo/Kif7b2b2254CloC57BL/6J-Kif7b2b2254Clo
Mutant 2254-002-1 shows abnormal gonad developmentKif7b2b2254Clo/Kif7b2b2254CloC57BL/6J-Kif7b2b2254Clo
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/30/2024
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