About   Help   FAQ
Phenotype Images associated with this Allele
Nomenclature
Symbol: Anks6b2b1801.1Clo
Name: ankyrin repeat and sterile alpha motif domain containing 6; Bench to Bassinet Program (B2B/CVDC), mutation 1801, subline 1 Cecilia Lo
MGI ID: MGI:5463579
Synonyms: Anks6Strkr, Streaker
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Mutant 1801-002-NA exhibits dextrocardia and dextrogastria with inverted liver lobation.b2b1801Clo/b2b1801CloC57BL/6J-b2b1801Clo
Anks6b2b1801.1Clo/Anks6b2b1801.1CloC57BL/6J-Anks6b2b1801.1Clo
Mutant 1801-002-NA exhibits abnormal right hemizygous venous connection.b2b1801Clo/b2b1801CloC57BL/6J-b2b1801Clo
Anks6b2b1801.1Clo/Anks6b2b1801.1CloC57BL/6J-Anks6b2b1801.1Clo
Serial micro-MRI image stack of 1801-002-NA in the coronal plane reveals heterotaxy, dextrocardia, right hemiazygous venous connection with left-side hepatic vein connects to left-side atrium, dextrogastria and inverted liver
Click thumbnail to play movie.		b2b1801Clo/b2b1801CloC57BL/6J-b2b1801Clo
Anks6b2b1801.1Clo/Anks6b2b1801.1CloC57BL/6J-Anks6b2b1801.1Clo
Serial 2D EFIC image stack of 1801-002-NA in the coronal plane reveals dextrocardia {I,L,L}, right hemiazygous venous connection, left ventricular hypertrophy
Click thumbnail to play movie.		b2b1801Clo/b2b1801CloC57BL/6J-b2b1801Clo
Anks6b2b1801.1Clo/Anks6b2b1801.1CloC57BL/6J-Anks6b2b1801.1Clo
EFIC Summaryb2b1801Clo/b2b1801CloC57BL/6J-b2b1801Clo
Anks6b2b1801.1Clo/Anks6b2b1801.1CloC57BL/6J-Anks6b2b1801.1Clo
Mutant 1801-003-NC exhibits dextrocardia with transposition of the great arteries (TGA) and right pulmonary isomerism.b2b1801Clo/b2b1801CloC57BL/6J-b2b1801Clo
Anks6b2b1801.1Clo/Anks6b2b1801.1CloC57BL/6J-Anks6b2b1801.1Clo
Mutant 1801-003-NC has dextrocardia with transposition of the great arteries (TGA), right pulmonary isomerism, inverted liver lobation, and dextrogastria.b2b1801Clo/b2b1801CloC57BL/6J-b2b1801Clo
Anks6b2b1801.1Clo/Anks6b2b1801.1CloC57BL/6J-Anks6b2b1801.1Clo
Serial 2D EFIC image stack of 1801-003-NC in the coronal plane reveals dextrocardia, transposition of the great arteries {I,L,L}, and abnormal lung lobation
Click thumbnail to play movie.		b2b1801Clo/b2b1801CloC57BL/6J-b2b1801Clo
Anks6b2b1801.1Clo/Anks6b2b1801.1CloC57BL/6J-Anks6b2b1801.1Clo
EFIC Summaryb2b1801Clo/b2b1801CloC57BL/6J-b2b1801Clo
Anks6b2b1801.1Clo/Anks6b2b1801.1CloC57BL/6J-Anks6b2b1801.1Clo
Mutant 1801-003-LA exhibits right lung isomerism (4R/3L) and duplicated inferior vena cava (IVC).b2b1801Clo/b2b1801CloC57BL/6J-b2b1801Clo
Anks6b2b1801.1Clo/Anks6b2b1801.1CloC57BL/6J-Anks6b2b1801.1Clo
Mutant 1801-003-LA exhibits anterior positioning of the aorta indicating transposition of the great arteries (TGA), duplicated inferior vena cava (IVC), and right pulmonary isomerism.b2b1801Clo/b2b1801CloC57BL/6J-b2b1801Clo
Anks6b2b1801.1Clo/Anks6b2b1801.1CloC57BL/6J-Anks6b2b1801.1Clo
Mutant 1801-003-LA shows dextrogastriab2b1801Clo/b2b1801CloC57BL/6J-b2b1801Clo
Anks6b2b1801.1Clo/Anks6b2b1801.1CloC57BL/6J-Anks6b2b1801.1Clo
Serial 2D EFIC image stack of 1801-003-LA in the coronal plane reveals heterotaxy, transposition of the great arteries {S,D,D}, atrioventricular septal defect (AVSD), duplicated inferior vena cava (IVC), and right lung isomerism
Click thumbnail to play movie.		b2b1801Clo/b2b1801CloC57BL/6J-b2b1801Clo
Anks6b2b1801.1Clo/Anks6b2b1801.1CloC57BL/6J-Anks6b2b1801.1Clo
EFIC Summaryb2b1801Clo/b2b1801CloC57BL/6J-b2b1801Clo
Anks6b2b1801.1Clo/Anks6b2b1801.1CloC57BL/6J-Anks6b2b1801.1Clo
Mutant 1801-005-LC exhibits heterotaxy with dextrocardia, transposition of the great arteries (TGA) with aorta positioned anteriorly, and right pulmonary isomerism with four lung lobes bilaterallyb2b1801Clo/b2b1801CloC57BL/6J-b2b1801Clo
Anks6b2b1801.1Clo/Anks6b2b1801.1CloC57BL/6J-Anks6b2b1801.1Clo
Serial 2D EFIC image stack of 1801-005-LC in the coronal plane reveals dextrocardia, TGA {I,L,L}, VSD, hypoplastic PA
Click thumbnail to play movie.		b2b1801Clo/b2b1801CloC57BL/6J-b2b1801Clo
Anks6b2b1801.1Clo/Anks6b2b1801.1CloC57BL/6J-Anks6b2b1801.1Clo
EFIC Summaryb2b1801Clo/b2b1801CloC57BL/6J-b2b1801Clo
Anks6b2b1801.1Clo/Anks6b2b1801.1CloC57BL/6J-Anks6b2b1801.1Clo
Mutant 1801-005-LB exhibits heterotaxy with dextrocardia and inverted lung lobation.b2b1801Clo/b2b1801CloC57BL/6J-b2b1801Clo
Anks6b2b1801.1Clo/Anks6b2b1801.1CloC57BL/6J-Anks6b2b1801.1Clo
Serial 2D EFIC image stack of 1801-005-LB in the coronal plane reveals dextrocardia, double outlet right ventricle (DORV) {I,L,L} with subaortic VSD
Click thumbnail to play movie.		b2b1801Clo/b2b1801CloC57BL/6J-b2b1801Clo
Anks6b2b1801.1Clo/Anks6b2b1801.1CloC57BL/6J-Anks6b2b1801.1Clo
EFIC Summaryb2b1801Clo/b2b1801CloC57BL/6J-b2b1801Clo
Anks6b2b1801.1Clo/Anks6b2b1801.1CloC57BL/6J-Anks6b2b1801.1Clo
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory