About   Help   FAQ
Phenotype Images associated with this Allele
Nomenclature
Symbol: Prdm1b2b1765Clo
Name: PR domain containing 1, with ZNF domain; Bench to Bassinet Program (B2B/CVDC), mutation 1765 Cecilia Lo
MGI ID: MGI:5446157
Synonyms: Jigsaw
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Mutant 1765-005-6 (E15.5) exhibits a hypoplastic LV and hypoplastic aortic arch.Prdm1b2b1765Clo/Prdm1b2b1765CloC57BL/6J-Prdm1b2b1765Clo
Mutant 1765-005-6 (E15.5) has a small hypertrophic LVPrdm1b2b1765Clo/Prdm1b2b1765CloC57BL/6J-Prdm1b2b1765Clo
EFIC SummaryPrdm1b2b1765Clo/Prdm1b2b1765CloC57BL/6J-Prdm1b2b1765Clo
Serial 2D EFIC image stack of 1765-005-6 (E15.5) in the coronal view shows suspected aortic valve atresia, hypertrophic obstructive cardiomyopathy, and small mitral annulus
Click thumbnail to play movie.		Prdm1b2b1765Clo/Prdm1b2b1765CloC57BL/6J-Prdm1b2b1765Clo
Mutant 1765-007-NA exhibits right aortic archPrdm1b2b1765Clo/Prdm1b2b1765CloC57BL/6J-Prdm1b2b1765Clo
EFIC summaryPrdm1b2b1765Clo/Prdm1b2b1765CloC57BL/6J-Prdm1b2b1765Clo
Serial 2D EFIC image stack of 1765-007-NA in the coronal plane reveals AVSD, right aortic arch, aberrant left subclavian artery from main PA
Click thumbnail to play movie.		Prdm1b2b1765Clo/Prdm1b2b1765CloC57BL/6J-Prdm1b2b1765Clo
Mutant 1765-005-1 (E15.5) shows malalignment of the great arteries with hypoplastic transverse arch and dilated pulmonary outflow.Prdm1b2b1765Clo/Prdm1b2b1765CloC57BL/6J-Prdm1b2b1765Clo
EFIC summaryPrdm1b2b1765Clo/Prdm1b2b1765CloC57BL/6J-Prdm1b2b1765Clo
Serial 2D EFIC image stack in the coronal plane of mutant 1765-005-1 (E15.5) reveals overriding aorta, AVSD, hypoplastic transverse aortic arch, and biventricular hypertrophy
Click thumbnail to play movie.		Prdm1b2b1765Clo/Prdm1b2b1765CloC57BL/6J-Prdm1b2b1765Clo
Mutant 1765-006-2 (E14.5) exhibits malalignment of the great arteries with abnormal right sided aortic arch (RAA) indicating possible vascular ring.Prdm1b2b1765Clo/Prdm1b2b1765CloC57BL/6J-Prdm1b2b1765Clo
EFIC summaryPrdm1b2b1765Clo/Prdm1b2b1765CloC57BL/6J-Prdm1b2b1765Clo
Serial 2D EFIC image stack in the coronal plane of mutant 1765-006-2 (E14.5) reveals double outlet right ventricle (DORV), right aortic arch (RAA), and vascular ring
Click thumbnail to play movie.		Prdm1b2b1765Clo/Prdm1b2b1765CloC57BL/6J-Prdm1b2b1765Clo
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory