Phenotype Images associated with this Allele - MGI

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Phenotype Images associated with this Allele

Nomenclature

Symbol:	Ccdc39^b2b1735Clo
Name:	coiled-coil domain containing 39; Bench to Bassinet Program (B2B/CVDC) mutation 1735, Cecilia Lo
MGI ID:	MGI:5438066
Synonyms:	Gonzo

Images for
Allele

Click images for details

Image	Caption	Genotypes involving this allele
Image	Caption	Allelic Composition	Genetic Background
	Mutant 1735-003-1 (E 15.5) displays dextrocardia and malpositioning of the atria and outflow tract with left pulmonary isomerism	Ccdc39^b2b1735Clo/Ccdc39^b2b1735Clo	C57BL/6J-Ccdc39^b2b1735Clo
	Mutant 1735-003-1 (E 15.5) displays malpositioning of the great arteries and atria	Ccdc39^b2b1735Clo/Ccdc39^b2b1735Clo	C57BL/6J-Ccdc39^b2b1735Clo
	EFIC Summary	Ccdc39^b2b1735Clo/Ccdc39^b2b1735Clo	C57BL/6J-Ccdc39^b2b1735Clo
	Serial 2D EFIC image stack of 1735-003-1 (E15.5) in the coronal plane reveals dextrocardia {A,L,L}, DORV, AVSD, hypoplastic transverse aorta forming vascular ring with ductus aterious, left pulmonary isomerism Click thumbnail to play movie.	Ccdc39^b2b1735Clo/Ccdc39^b2b1735Clo	C57BL/6J-Ccdc39^b2b1735Clo
	Mutant 1735-003-1 presents with heterotaxy indicated by dextrocardia and dextrogastria	Ccdc39^b2b1735Clo/Ccdc39^b2b1735Clo	C57BL/6J-Ccdc39^b2b1735Clo
	Mutant 1735-002-LA displays situs inversus totalis indicated by dextrocardia, reverse lung and liver lobation, and dextrogastria	Ccdc39^b2b1735Clo/Ccdc39^b2b1735Clo	C57BL/6J-Ccdc39^b2b1735Clo
	Mutant 1735-002-LA reveals dextrocardia with right aortic arch and reversal of lung lobation	Ccdc39^b2b1735Clo/Ccdc39^b2b1735Clo	C57BL/6J-Ccdc39^b2b1735Clo
	Videomicroscopy of mutant 1735-002-LA reveals immotile airway cilia Click thumbnail to play movie.	Ccdc39^b2b1735Clo/Ccdc39^b2b1735Clo	C57BL/6J-Ccdc39^b2b1735Clo
	Mutant 1735-002-LC displays situs inversus totalis with dextrocardia, reverse lung and liver lobation, and dextrogastria	Ccdc39^b2b1735Clo/Ccdc39^b2b1735Clo	C57BL/6J-Ccdc39^b2b1735Clo
	Mutant 1735-002-LC displays mirror image dextrocardia and reversed lung lobation pattern	Ccdc39^b2b1735Clo/Ccdc39^b2b1735Clo	C57BL/6J-Ccdc39^b2b1735Clo
	EFIC Summary	Ccdc39^b2b1735Clo/Ccdc39^b2b1735Clo	C57BL/6J-Ccdc39^b2b1735Clo
	Serial 2D EFIC image stack of 1735-002-LC in the coronal plane reveals mirror image dextrocardia Click thumbnail to play movie.	Ccdc39^b2b1735Clo/Ccdc39^b2b1735Clo	C57BL/6J-Ccdc39^b2b1735Clo
	Mutant 1735-002-LC exhibits micrognathia and short snout	Ccdc39^b2b1735Clo/Ccdc39^b2b1735Clo	C57BL/6J-Ccdc39^b2b1735Clo

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