 | Mutant 1146-012-LA displays transposition of the great arteries (TGA) with abnormal lung lobation | b2b1146Clo/b2b1146Clo | C57BL/6J-b2b1146Clo |
 | EFIC Summary | b2b1146Clo/b2b1146Clo | C57BL/6J-b2b1146Clo |
 | Serial 2D EFIC image stack in the coronal plane of 1146-012-LA reveals Taussig-Being DORV {S,D,D}, atrioventricular septal defect (AVSD), right aortic arch, right lung isomerism
Click thumbnail to play movie. | b2b1146Clo/b2b1146Clo | C57BL/6J-b2b1146Clo |
 | Mutant 1146-012-LA displays malaligned sternal vertebrae | b2b1146Clo/b2b1146Clo | C57BL/6J-b2b1146Clo |
 | Mutant 1146-012-LA displays hypoplastic thymus, levocardia with anterior positioning of the aorta, midline liver and left pulmonary isomerism, indicating heterotaxy | b2b1146Clo/b2b1146Clo | C57BL/6J-b2b1146Clo |
 | Mutant 1146-02-LA displays dextrogastria | b2b1146Clo/b2b1146Clo | C57BL/6J-b2b1146Clo |
 | Videomicroscopy of 1146-012-LA mutant airway reveals motile cilia
Click thumbnail to play movie. | b2b1146Clo/b2b1146Clo | C57BL/6J-b2b1146Clo |
 | Mutant 1146-007-5 (E15.5) displays right aortic arch with right sided inferior vena cava (IVC) | b2b1146Clo/b2b1146Clo | C57BL/6J-b2b1146Clo |
 | Mutant 1146-007-5 (E 15.5) displays right aortic arch with transposition of the great arteries (TGA) and right sided inferior vena cava (IVC) | b2b1146Clo/b2b1146Clo | C57BL/6J-b2b1146Clo |
 | Mutant 1146-007-5 (E 15.5) displays abnormal 3 lung lobes on each side, indicating right isomerism | b2b1146Clo/b2b1146Clo | C57BL/6J-b2b1146Clo |
 | EFIC Summary | b2b1146Clo/b2b1146Clo | C57BL/6J-b2b1146Clo |
 | Serial 2D EFIC image stack in the coronal view of animal 1146-007-5 (E15.5) reveals Taussig-Bing DORV with unbalanced AVSD {S,D,D}, small LV, and right aortic arch
Click thumbnail to play movie. | b2b1146Clo/b2b1146Clo | C57BL/6J-b2b1146Clo |
 | Mutant 1146-015-LA displays dextroversion of the heart and inverted liver lobation, indicating heterotaxy | b2b1146Clo/b2b1146Clo | C57BL/6J-b2b1146Clo |
 | EFIC Summary | b2b1146Clo/b2b1146Clo | C57BL/6J-b2b1146Clo |
 | Serial 2D EFIC image stack in the coronal plane of 1146-015-LA reveals dextroversion, discordant Taussig-Bing type DORV {I,D,D}, AVSD, muscular VSD, left side IVC, and right isomerism lung
Click thumbnail to play movie. | b2b1146Clo/b2b1146Clo | C57BL/6J-b2b1146Clo |
 | Mutant 1146-012-NA exhibits transposition of the great arteries (TGA) with right aortic arch (RAA), left sided IVC, right lung isomerism, midline liver lobation, indicating heterotaxy | b2b1146Clo/b2b1146Clo | C57BL/6J-b2b1146Clo |
 | Mutant 1146-012-NA displays right aortic arch with anterior positioning of the great arteries and right lung isomerism. | b2b1146Clo/b2b1146Clo | C57BL/6J-b2b1146Clo |
 | 2D micro CT image stack in the coronal plane of 1146-012-NA reveals hetertaxy, levocardia, TGA, AVSD {I,D,D}, right aortic arch, TAPVR, left side IVC, right isomerism lung, mid-line liver, dextrogastria
Click thumbnail to play movie. | b2b1146Clo/b2b1146Clo | C57BL/6J-b2b1146Clo |
 | Mutant 1146-007-1 (E 15.5) displays dextrocardia and anterior positioning of the aorta with left lung isomerism | b2b1146Clo/b2b1146Clo | C57BL/6J-b2b1146Clo |
 | EFIC Summary | b2b1146Clo/b2b1146Clo | C57BL/6J-b2b1146Clo |
 | Serial 2D EFIC image stack in the coronal plane of 1146-007-1 (E15.5) reveals dextrocardia, Taussig-Bing DORV, AVSD, with juxtaposition of atrium (RA up and LA low) {I,L,L}, TAPVR. hypoplastic transverse aorta left lung isomerism
Click thumbnail to play movie. | b2b1146Clo/b2b1146Clo | C57BL/6J-b2b1146Clo |
 | Mutant 1146-007-1 (E 15.5) displays glomerular cysts | b2b1146Clo/b2b1146Clo | C57BL/6J-b2b1146Clo |
 | Mutant 1146-007-1 (E 15.5) displays short, knobby cilia (green) within the ureteric bud | b2b1146Clo/b2b1146Clo | C57BL/6J-b2b1146Clo |
 | Mutant 1146-007-1 (E 15.5) displays short, knobby cilia (red) within the renal corpuscle | b2b1146Clo/b2b1146Clo | C57BL/6J-b2b1146Clo |
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