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Phenotype Images associated with this Allele
Nomenclature
Symbol: Porcntm1.1Vdv
Name: porcupine O-acyltransferase; targeted mutation 1.1, Ignatia B Van den Veyver
MGI ID: MGI:5435556
Synonyms: Porcn-ex3-7flox
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Open neural tube and abdominal wall closure defect in Porcntm1.1Vdv/Porcn+ Hprt1tm1(CAG-cre)Mnn/Hprt1+ micePorcntm1.1Vdv/Porcn+
Hprt1tm1(CAG-cre)Mnn/Hprt1+
involves: 129S/Sv * C57BL/6J
Skeletal abnormalities in Porcntm1.1Vdv/Y Tg(Prrx1-cre)1Cjt/0 micePorcntm1.1Vdv/Y
Tg(Prrx1-cre)1Cjt/0
involves: 129S4/SvJaeSor * 129S5/SvEvBrd * C57BL/6 * SJL/J
Dental and skin abnormalities and alopecia in Porcntm1.1Vdv/Y Tg(KRT14-cre)1Efu/0 micePorcntm1.1Vdv/Y
Tg(KRT14-cre)1Efu/0
involves: 129S4/SvJaeSor * 129S5/SvEvBrd * C57BL/6J
Subcutaneous fat in Porcntm1.1Vdv/Y Tg(KRT14-cre)1Efu/0 mice is directly adjacent to the outermost epidermal layers of the skinPorcntm1.1Vdv/Y
Tg(KRT14-cre)1Efu/0
involves: 129S4/SvJaeSor * 129S5/SvEvBrd * C57BL/6J

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory