About   Help   FAQ
Phenotype Images associated with this Allele
Nomenclature
Symbol: Ap1b1b2b1660Clo
Name: adaptor protein complex AP-1, beta 1 subunit; Bench to Bassinet Program (B2B/CVDC), mutation 1660 Cecilia Lo
MGI ID: MGI:5433323
Synonyms: Pistachio
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Mutant 11660-002-LA exhibits dextrocardia with situs inversus and possible bile duct obstructionAp1b1b2b1660Clo/Ap1b1b2b1660CloC57BL/6J-Ap1b1b2b1660Clo
Mutant 1660-002-LA exhibits dextrogastriaAp1b1b2b1660Clo/Ap1b1b2b1660CloC57BL/6J-Ap1b1b2b1660Clo
Mutant 1660-002-LA with mirror image dextrocardia with inverted lung lobationAp1b1b2b1660Clo/Ap1b1b2b1660CloC57BL/6J-Ap1b1b2b1660Clo
Mutant 160-002-LA with hypoplastic spleenAp1b1b2b1660Clo/Ap1b1b2b1660CloC57BL/6J-Ap1b1b2b1660Clo
Mutant 1660-002-LA with malaligned sternovertebraeAp1b1b2b1660Clo/Ap1b1b2b1660CloC57BL/6J-Ap1b1b2b1660Clo
Mutant 1660-002-LA showing abormal kidney positioning at the same anterior-posterior levelAp1b1b2b1660Clo/Ap1b1b2b1660CloC57BL/6J-Ap1b1b2b1660Clo
Tracheal airway epithelia from mutant 1660-002-LA show dyskinetic ciliary motion
Click thumbnail to play movie.		Ap1b1b2b1660Clo/Ap1b1b2b1660CloC57BL/6J-Ap1b1b2b1660Clo
Mutant 1660-003-LA exhibits levocardia and normal liver situs, but with left pulmonary isomerismAp1b1b2b1660Clo/Ap1b1b2b1660CloC57BL/6J-Ap1b1b2b1660Clo
Mutant 1660-003-LA exhibits aspleniaAp1b1b2b1660Clo/Ap1b1b2b1660CloC57BL/6J-Ap1b1b2b1660Clo
Mutant 1660-003-LA exhibits abnormal positioning of both kidneys at same anterior-posterior axial levelAp1b1b2b1660Clo/Ap1b1b2b1660CloC57BL/6J-Ap1b1b2b1660Clo
EFIC SummaryAp1b1b2b1660Clo/Ap1b1b2b1660CloC57BL/6J-Ap1b1b2b1660Clo
Serial 2D EFIC image stack in the coronal plane of 1660-003-LA reveals bilateral IVC, bilateral single lung lobe
Click thumbnail to play movie.		Ap1b1b2b1660Clo/Ap1b1b2b1660CloC57BL/6J-Ap1b1b2b1660Clo
Mutant 1660-003-LA respiratory epithelia show areas of dyskinetic cilia motility and immotile cilia
Click thumbnail to play movie.		Ap1b1b2b1660Clo/Ap1b1b2b1660CloC57BL/6J-Ap1b1b2b1660Clo
Tracheal airway epithelia from mutant 1660-003-LA show dyskinetic ciliary motility
Click thumbnail to play movie.		Ap1b1b2b1660Clo/Ap1b1b2b1660CloC57BL/6J-Ap1b1b2b1660Clo
Mutant 1660-003-LB exhibits aspleniaAp1b1b2b1660Clo/Ap1b1b2b1660CloC57BL/6J-Ap1b1b2b1660Clo
Mutant 1660-003-LB exhibits malaligned sternovertebraeAp1b1b2b1660Clo/Ap1b1b2b1660CloC57BL/6J-Ap1b1b2b1660Clo
Mutant 1660-004-LA exhibits situs inversus totalisAp1b1b2b1660Clo/Ap1b1b2b1660CloC57BL/6J-Ap1b1b2b1660Clo
Mutant 1660-004-LA exhibits hypoplastic spleenAp1b1b2b1660Clo/Ap1b1b2b1660CloC57BL/6J-Ap1b1b2b1660Clo
Mutant 1660-004-LA exhibits hypoplastic spleenAp1b1b2b1660Clo/Ap1b1b2b1660CloC57BL/6J-Ap1b1b2b1660Clo
Mutant 1660-004-LA exhibits abnormal kidney situs bilaterally at the anterior-posterior levelAp1b1b2b1660Clo/Ap1b1b2b1660CloC57BL/6J-Ap1b1b2b1660Clo
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory