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Phenotype Images associated with this Allele
Nomenclature
Symbol: b2b1519Clo
Name: Mutant line 1519; Bench to Bassinet Program (B2B/CVDC), mutation 1519 Cecilia Lo
MGI ID: MGI:5433294
Synonyms: Mellow Yellow
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Mutant 1519-005-LA exhibits situs inversus totalisb2b1519Clo/b2b1519CloC57BL/6J-b2b1519Clo
Mutant 1519-005-LA exhibits dextrogastria with hypoplastic spleenb2b1519Clo/b2b1519CloC57BL/6J-b2b1519Clo
Mutant 1519-005-LA exhibits mirror image dextracardia with inverted lung lobationb2b1519Clo/b2b1519CloC57BL/6J-b2b1519Clo
Mutant 1519-005-LA exhibits malaligned sternovertebraeb2b1519Clo/b2b1519CloC57BL/6J-b2b1519Clo
EFIC Summaryb2b1519Clo/b2b1519CloC57BL/6J-b2b1519Clo
Serial 2D EFIC image stack in the coronal plane of 1519-005-LA reveals dextrocardiac mirror image heart {ILI} and lung lobation pattern
Click thumbnail to play movie.		b2b1519Clo/b2b1519CloC57BL/6J-b2b1519Clo
1591-005-LA tracheal epithelia exhibits normal cilia motility
Click thumbnail to play movie.		b2b1519Clo/b2b1519CloC57BL/6J-b2b1519Clo
Mutant 1519-004-LA exhibits situs inversus totalisb2b1519Clo/b2b1519CloC57BL/6J-b2b1519Clo
Mutant 1519-004-LA exhibits mirror symmetric dextrocardia with inverted lung lobation and right sided stomach and spleenb2b1519Clo/b2b1519CloC57BL/6J-b2b1519Clo
Mutant 1519-004-LA shows inverted anterior-posterior positioning of the left/right kidneysb2b1519Clo/b2b1519CloC57BL/6J-b2b1519Clo
Mutant 1519-006-3 (E15.5) exhibits situs inversus totalis with dextrocardia, inverted lung lobation and inverted liver situsb2b1519Clo/b2b1519CloC57BL/6J-b2b1519Clo
Mutant 1519-006-3 (E15.5) with mirror symmetric dextrocardia with inverted lung lobationb2b1519Clo/b2b1519CloC57BL/6J-b2b1519Clo
EFIC Summaryb2b1519Clo/b2b1519CloC57BL/6J-b2b1519Clo
Serial 2D EFIC image stack of mutant 1519-006-3 (E15.5) shows mirror image dextrocardia, hypoplastic mRV, tricuspid stenosis
Click thumbnail to play movie.		b2b1519Clo/b2b1519CloC57BL/6J-b2b1519Clo
Serial 2D micro-CT image stack in the coronal plane of 1519-006-3 (E15.5) reveals situs inversus totalis
Click thumbnail to play movie.		b2b1519Clo/b2b1519CloC57BL/6J-b2b1519Clo
Mutant 1519-006-7 (E15.5) exhibits mesocardia, with enlarged and malpositioned atria and abnormally positioned thymusb2b1519Clo/b2b1519CloC57BL/6J-b2b1519Clo
Mutant 1519-006-7 (E15.5) exhibits mesocardia with right sided arch, malaligned great arteries and left pulmonary isomerismb2b1519Clo/b2b1519CloC57BL/6J-b2b1519Clo
EFIC Summaryb2b1519Clo/b2b1519CloC57BL/6J-b2b1519Clo
Serial 2D EFIC image stack in the coronal plane of 1519-006-7 shows hyoplastic RV with unbalanced AVSD, muscular VSD (mVSD), perimembranous VSD, vascular sling and left lung isomerism
Click thumbnail to play movie.		b2b1519Clo/b2b1519CloC57BL/6J-b2b1519Clo
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory