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Phenotype Images associated with this Allele
Nomenclature
Symbol: Dnai1b2b1526Clo
Name: dynein axonemal intermediate chain 1; Bench to Bassinet Program (B2B/CVDC), mutation 1526 Cecilia Lo
MGI ID: MGI:5317589
Synonyms: Spot
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Mutant 1526-007-NA exhibits heterotaxy with dextrocardia, dual IVC, left lung isomerism (2R/2L), stenotic transverse aortic arch, and thickened ventricular walls which is diagnosed as biventricular hypertrophy by EFIC imagingDnai1b2b1526Clo/Dnai1b2b1526CloC57BL/6J-Dnai1b2b1526Clo
EFIC SummaryDnai1b2b1526Clo/Dnai1b2b1526CloC57BL/6J-Dnai1b2b1526Clo
Serial 2D EFIC image stack in the coronal plane of 1526-007-NA reveals mirror image dextrocardia, biventricular hypertrophy, stenosis of transverse arch, and dual IVC
Click thumbnail to play movie.
Dnai1b2b1526Clo/Dnai1b2b1526CloC57BL/6J-Dnai1b2b1526Clo
Mutant 1526-007-NA presents with a short snout and microganthiaDnai1b2b1526Clo/Dnai1b2b1526CloC57BL/6J-Dnai1b2b1526Clo
Mutant 1526-007-NA shows a malaligned sternumDnai1b2b1526Clo/Dnai1b2b1526CloC57BL/6J-Dnai1b2b1526Clo
Mutant 1526-007-LC exhibits situs inversus totalis, which is indicated by dextrocardia with dextrogastriaDnai1b2b1526Clo/Dnai1b2b1526CloC57BL/6J-Dnai1b2b1526Clo
Mutant 1526-007-LC shows immotile tracheal airway cilia
Click thumbnail to play movie.
Dnai1b2b1526Clo/Dnai1b2b1526CloC57BL/6J-Dnai1b2b1526Clo
Mutant 1526-007-LA exhibits heterotaxy with dextrocardia, normal lung lobation, left liver isomerism (2R/2L), and levogastriaDnai1b2b1526Clo/Dnai1b2b1526CloC57BL/6J-Dnai1b2b1526Clo
EFIC SummaryDnai1b2b1526Clo/Dnai1b2b1526CloC57BL/6J-Dnai1b2b1526Clo
Serial 2D EFIC image stack in the coronal plane of 1526-007-LA reveals mirror image dextrocardia
Click thumbnail to play movie.
Dnai1b2b1526Clo/Dnai1b2b1526CloC57BL/6J-Dnai1b2b1526Clo
Mutant 1526-007-LA presents with a hypoplastic spleenDnai1b2b1526Clo/Dnai1b2b1526CloC57BL/6J-Dnai1b2b1526Clo
Mutant 1526-007-LA exhibits a short snout and microganthiaDnai1b2b1526Clo/Dnai1b2b1526CloC57BL/6J-Dnai1b2b1526Clo

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory