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Phenotype Images associated with this Allele
Nomenclature
Symbol: b2b498Clo
Name: Mutant line 498; Bench to Bassinet Program (B2B/CVDC), mutation 498 Cecilia Lo
MGI ID: MGI:5313713
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
2D serial EFIC image stack of 498-003-3 (E18.5) in the coronral view reveals pulmonary atresia, perimembranous and muscular VSD, right MAPCA, and hypoplastic lung.
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b2b498Clo/b2b498CloC57BL/6J-b2b498Clo
2D serial EFIC image stack of mutant 498-003-3 (E18.5) in the transverse view reveals pulmonary atresia, perimembranous VSD (pmVSD), muscular VSD (mVSD), and hypoplastic lung.
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b2b498Clo/b2b498CloC57BL/6J-b2b498Clo
3D EFIC reconstruction of mutant 498-003-1 (E18.5) shows pulmonary atresia, right MAPCA, and hypoplastic lung.b2b498Clo/b2b498CloC57BL/6J-b2b498Clo
3D EFIC reconstruction of mutant 498-003-1 shows pulmonary atresia with right MAPCA and hypoplastic lung.
Click thumbnail to play movie.
b2b498Clo/b2b498CloC57BL/6J-b2b498Clo
2D serial EFIC image stack of mutant 498-003-1 (E18.5) in the coronal view reveals pulmonary atresia with right MAPCA and hypoplastic lung.
Click thumbnail to play movie.
b2b498Clo/b2b498CloC57BL/6J-b2b498Clo
Color flow imaging in sagittal view showed VSD with common trunk over the ventricular septum, suggesting PTA or pulmonary atresia with VSD.
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b2b498Clo/b2b498CloC57BL/6J-b2b498Clo
Ultrasound 2D imaging of 498-003-1 fetus in the frontal view showed heart apex pointing to the middle, indicating mesocardia.
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b2b498Clo/b2b498CloC57BL/6J-b2b498Clo
Ultrasound 2D imaging in the frontal view of fetus 498-003-1 (E18.5) showed biventricular hypertrophy
Click thumbnail to play movie.
b2b498Clo/b2b498CloC57BL/6J-b2b498Clo
Color flow ultrasound imaging of fetus 498-003-1 (E18.5) in sagittal view showed VSD, common trunk over the ventricular septum, indicating PTA or pulmonary atresia with VSD.b2b498Clo/b2b498CloC57BL/6J-b2b498Clo
EFIC summaryb2b498Clo/b2b498CloC57BL/6J-b2b498Clo

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory