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Phenotype Images associated with this Allele
Nomenclature
Symbol: Mmp21b2b873Clo
Name: matrix metallopeptidase 21; Bench to Bassinet Program (B2B/CVDC), mutation 873 Cecilia Lo
MGI ID: MGI:5311376
Synonyms: c.G530T, Miri, Miri (line 873), p.Trp177Leu
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Dextrocardia with anterior aorta, right pulmonary isomerism with bilateral 3 lung lobes, and mirror symmetric liver situs.Mmp21b2b873Clo/Mmp21b2b873CloC57BL/6J-Mmp21b2b873Clo
Heterotaxy indicated by dextrocardia, transposition of the great artery (TGA), right pulmonary isomerism, and mirror symmetric abdominal organ situs.Mmp21b2b873Clo/Mmp21b2b873CloC57BL/6J-Mmp21b2b873Clo
2D serial EFIC images in the coronal view reveals dextrocardia {S(A), D, D}, and tricuspid atresia type IIc (transposition)
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Mmp21b2b873Clo/Mmp21b2b873CloC57BL/6J-Mmp21b2b873Clo
2D serial EFIC images in the transverse view reveals LV inlet and mitral valve
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Mmp21b2b873Clo/Mmp21b2b873CloC57BL/6J-Mmp21b2b873Clo
3D EFIC volume rendering reveals left-sided IVC
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Mmp21b2b873Clo/Mmp21b2b873CloC57BL/6J-Mmp21b2b873Clo
Mmp21b2b873Clo/Mmp21b2b873CloC57BL/6J-Mmp21b2b873Clo
2D MRI image stack in the coronal plane of 873-026-NA reveals TGA, VSD
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Mmp21b2b873Clo/Mmp21b2b873CloC57BL/6J-Mmp21b2b873Clo

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory