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Phenotype Images associated with this Allele
Nomenclature
Symbol: Myo5btm1a(KOMP)Wtsi
Name: myosin VB; targeted mutation 1a, Wellcome Trust Sanger Institute
MGI ID: MGI:4461468
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Wrinkled skin and evidence of diarrhea in Myo5btm1a(KOMP)Wtsi/Myo5btm1a(KOMP)Wtsi newbornsMyo5btm1a(KOMP)Wtsi/Myo5btm1a(KOMP)WtsiC57BL/6N-Myo5btm1a(KOMP)Wtsi
Ultrastructural defects in the intestinal epithelium of Myo5btm1a(KOMP)Wtsi/Myo5btm1a(KOMP)Wtsi E20 embryosMyo5btm1a(KOMP)Wtsi/Myo5btm1a(KOMP)WtsiC57BL/6N-Myo5btm1a(KOMP)Wtsi
Shorter microvilli and a subapical region lacking microvesicle trafficking in Myo5btm1a(KOMP)Wtsi/Myo5btm1a(KOMP)Wtsi enterocytesMyo5btm1a(KOMP)Wtsi/Myo5btm1a(KOMP)WtsiC57BL/6N-Myo5btm1a(KOMP)Wtsi

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory