About   Help   FAQ
Phenotype Images associated with this Allele
Nomenclature
Symbol: Stac3tm1a(KOMP)Wtsi
Name: SH3 and cysteine rich domain 3; targeted mutation 1a, Wellcome Trust Sanger Institute
MGI ID: MGI:4365152
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Abnormalities of Stac3tm1a(KOMP)Wtsi/Stac3tm1a(KOMP)Wtsi miceStac3tm1a(KOMP)Wtsi/Stac3tm1a(KOMP)Wtsiinvolves: C57BL/6N
Normal neuromuscular junction formation but increased nerve branching in Stac3tm1a(KOMP)Wtsi/Stac3tm1a(KOMP)Wtsi miceStac3tm1a(KOMP)Wtsi/Stac3tm1a(KOMP)Wtsiinvolves: C57BL/6N
Decreased bone development at muscle insertion sites in Stac3tm1a(KOMP)Wtsi/Stac3tm1a(KOMP)Wtsi miceStac3tm1a(KOMP)Wtsi/Stac3tm1a(KOMP)Wtsiinvolves: C57BL/6N
Disorganization of sarcomeres in E18.5 Stac3tm1a(KOMP)Wtsi/Stac3tm1a(KOMP)Wtsi tonguesStac3tm1a(KOMP)Wtsi/Stac3tm1a(KOMP)Wtsiinvolves: C57BL/6N
Curved body shape and dropping forelimbs in Stac3tm1a(KOMP)Wtsi/Stac3tm1a(KOMP)Wtsi mutantsStac3tm1a(KOMP)Wtsi/Stac3tm1a(KOMP)WtsiB6(Cg)-Stac3tm1a(KOMP)Wtsi
Abnormal skeletal muscle morphology in Stac3tm1a(KOMP)Wtsi/Stac3tm1a(KOMP)Wtsi newbornsStac3tm1a(KOMP)Wtsi/Stac3tm1a(KOMP)WtsiB6(Cg)-Stac3tm1a(KOMP)Wtsi
Myofibers of Stac3tm1a(KOMP)Wtsi/Stac3tm1a(KOMP)Wtsi mice have fewer, smaller, and disorganized myofibrilsStac3tm1a(KOMP)Wtsi/Stac3tm1a(KOMP)WtsiB6(Cg)-Stac3tm1a(KOMP)Wtsi

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/30/2024
MGI 6.23
The Jackson Laboratory