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Phenotype Images associated with this Allele
Nomenclature
Symbol: Ehd4tm1.1Haba
Name: EH-domain containing 4; targeted mutation 1.1, Hamid Band
MGI ID: MGI:4360181
Synonyms: Ehd4-
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Smaller size and pale, small kidneys in Ehd3tm1.2Haba/Ehd3tm1.2Haba Ehd4tm1.1Haba/Ehd4tm1.1Haba miceEhd3tm1.2Haba/Ehd3tm1.2Haba
Ehd4tm1.1Haba/Ehd4tm1.1Haba		involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J
Thrombotic microangiopathy in Ehd3tm1.2Haba/Ehd3tm1.2Haba Ehd4tm1.1Haba/Ehd4tm1.1Haba miceEhd3tm1.2Haba/Ehd3tm1.2Haba
Ehd4tm1.1Haba/Ehd4tm1.1Haba		involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J
Ultrastructural changes in Ehd3tm1.2Haba/Ehd3tm1.2Haba Ehd4tm1.1Haba/Ehd4tm1.1Haba glomeruliEhd3tm1.2Haba/Ehd3tm1.2Haba
Ehd4tm1.1Haba/Ehd4tm1.1Haba		involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J
Increased apoptosis in Ehd3tm1.2Haba/Ehd3tm1.2Haba Ehd4tm1.1Haba/Ehd4tm1.1Haba glomeruliEhd3tm1.2Haba/Ehd3tm1.2Haba
Ehd4tm1.1Haba/Ehd4tm1.1Haba		involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J
Reduced testicular size in Ehd4tm1.1Haba/Ehd4tm1.1Haba miceEhd4tm1.1Haba/Ehd4tm1.1Habainvolves: C57BL/6 * C57BL/6J * FVB/N
Progressive reduction of seminiferous tubule diameter with increasing age in Ehd4tm1.1Haba/Ehd4tm1.1Haba miceEhd4tm1.1Haba/Ehd4tm1.1Habainvolves: C57BL/6 * C57BL/6J * FVB/N
Increase in apoptosis in Ehd4tm1.1Haba/Ehd4tm1.1Haba testisEhd4tm1.1Haba/Ehd4tm1.1Habainvolves: C57BL/6 * C57BL/6J * FVB/N
Increase in PCNA-positive cells in Ehd4tm1.1Haba/Ehd4tm1.1Haba miceEhd4tm1.1Haba/Ehd4tm1.1Habainvolves: C57BL/6 * C57BL/6J * FVB/N
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory