Phenotype Images associated with this Allele - MGI

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Phenotype Images associated with this Allele

Nomenclature

Symbol:	Sgpp1^{tm1(KOMP)Vlcg}
Name:	sphingosine-1-phosphate phosphatase 1; targeted mutation 1, Velocigene
MGI ID:	MGI:3808500
Synonyms:	Sgpp1^tm1Vlcg

Images for
Allele

Click images for details

Image	Caption	Genotypes involving this allele
Image	Caption	Allelic Composition	Genetic Background
	Sgpp2^tm1Rlp/Sgpp2^tm1Rlp mice showed normal skin appearance similar to wild-type mice, in contrast to severe ichtyosis in Sgpp1^{tm1(KOMP)Vlcg}/Sgpp1^{tm1(KOMP)Vlcg} mice	Sgpp1^{tm1(KOMP)Vlcg}/Sgpp1^{tm1(KOMP)Vlcg}	involves: C57BL/6NTac
		Sgpp2^tm1Rlp/Sgpp2^tm1Rlp	B6.129S6-Sgpp2^tm1Rlp
	Sgpp1^{tm1(KOMP)Vlcg}/Sgpp1^{tm1(KOMP)Vlcg} pups exhibit focal desquamation and abnormal epidermal histology	Sgpp1^{tm1(KOMP)Vlcg}/Sgpp1^{tm1(KOMP)Vlcg}	involves: C57BL/6NTac
	Abnormal skin in surviving Sgpp1^{tm1(KOMP)Vlcg}/Sgpp1^{tm1(KOMP)Vlcg} adult mice	Sgpp1^{tm1(KOMP)Vlcg}/Sgpp1^{tm1(KOMP)Vlcg}	involves: C57BL/6NTac

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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