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Phenotype Images associated with this Allele
Nomenclature
Symbol: Upk2tm1Tsun
Name: uroplakin 2; targeted mutation 1, Tung-Tien Sun
MGI ID: MGI:3527893
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Upk2tm1Tsun/Upk2tm1Tsun urothelium lacks a typical umbrella cell layer and becomes hyperplasticUpk2tm1Tsun/Upk2tm1Tsuninvolves: 129S/SvEv * Black Swiss
Upk2tm1Tsun/Upk2tm1Tsun urothelium has small superficial cells and a particle-free apical surfaceUpk2tm1Tsun/Upk2tm1Tsuninvolves: 129S/SvEv * Black Swiss
Upk2tm1Tsun/Upk2tm1Tsun mice display hydronephrosis and renal abnormalitiesUpk2tm1Tsun/Upk2tm1Tsuninvolves: 129S/SvEv * Black Swiss
Upk2tm1Tsun/Upk2tm1Tsun mice exhibit ureteral obstructionUpk2tm1Tsun/Upk2tm1Tsuninvolves: 129S/SvEv * Black Swiss
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory