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Phenotype Images associated with this Allele
Nomenclature
Symbol: Jam3tm1Rha
Name: junction adhesion molecule 3; targeted mutation 1, Ralf H Adams
MGI ID: MGI:3055281
Synonyms: Jam-C-
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Small body size, severe hydrocephalus, and brain alterations in Jam3tm1Rha/Jam3tm1Rha miceJam3tm1Rha/Jam3tm1RhaB6.129P2-Jam3tm1Rha
Hydrocephalus develops over time in Jam3tm1Rha/Jam3tm1Rha miceJam3tm1Rha/Jam3tm1RhaB6.129P2-Jam3tm1Rha
Reactive gliosis in Jam3tm1Rha/Jam3tm1Rha mice with hydrocephalusJam3tm1Rha/Jam3tm1RhaB6.129P2-Jam3tm1Rha
Loss of cortical layering in the brains of Jam3tm1Rha/Jam3tm1Rha mice with hydrocephalusJam3tm1Rha/Jam3tm1RhaB6.129P2-Jam3tm1Rha
Hemorrhages within the brain of Jam3tm1Rha/Jam3tm1Rha mice with hydrocephalusJam3tm1Rha/Jam3tm1RhaB6.129P2-Jam3tm1Rha
Impaired cerebrospinal fluid drainage from the lateral to the 3rd ventricle in Jam3tm1Rha/Jam3tm1Rha mice with hydrocephalusJam3tm1Rha/Jam3tm1RhaB6.129P2-Jam3tm1Rha
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory