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Phenotype Images associated with this Allele
Nomenclature
Symbol: Lama4tm1Ktry
Name: laminin, alpha 4; targeted mutation 1, Karl Tryggvason
MGI ID: MGI:2179127
Synonyms: Lama4-, Lama4tm1Blp
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Cardiac hypertrophy and cardiomyocyte hypertrophy in Lama4tm1Ktry/Lama4tm1Ktry miceLama4tm1Ktry/Lama4tm1KtryB6.129X1-Lama4tm1Ktry
Impaired cardiac function in Lama4tm1Ktry/Lama4tm1Ktry mice at the age of 36-40 weeksLama4tm1Ktry/Lama4tm1KtryB6.129X1-Lama4tm1Ktry
Lama4tm1Ktry/Lama4tm1Ktry hearts exhibit cardiomyocyte degeneration and fibrosis with ageLama4tm1Ktry/Lama4tm1KtryB6.129X1-Lama4tm1Ktry
Cardiomyocyte degeneration and fibrosis in the 40 week old Lama4tm1Ktry/Lama4tm1Ktry heartLama4tm1Ktry/Lama4tm1KtryB6.129X1-Lama4tm1Ktry
Amyelinating peripheral neuropathies in Lama4tm1Ktry/Lama4tm1Ktry and Lama2dy-2J/Lama2dy-2J miceLama4tm1Ktry/Lama4tm1KtryB6.129X1-Lama4tm1Ktry
Lama2dy-2J/Lama2dy-2JB6.WK-Lama2dy-2J/J
Origin and distribution of amyelination in Lama2dy-2J/Lama2dy-2J and Lama4tm1Ktry/Lama4tm1Ktry miceLama4tm1Ktry/Lama4tm1KtryB6.129X1-Lama4tm1Ktry
Lama2dy-2J/Lama2dy-2JB6.WK-Lama2dy-2J/J
Severe neuropathy in Lama2dy-2J/Lama2dy-2J Lama4tm1Ktry/Lama4tm1Ktry miceLama2dy-2J/Lama2dy-2J
Lama4tm1Ktry/Lama4tm1Ktry		involves: 129X1/SvJ * C57BL/6 * WK/ReJ
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory