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Phenotype Images associated with this Allele
Nomenclature
Symbol: Thbs2tm1Bst
Name: thrombospondin 2; targeted mutation 1, Paul Bornstein
MGI ID: MGI:2153006
Synonyms: Thbs2-, Tsp-2-, TSP2-
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Thbs2tm1Bst/Thbs2tm1Bst mice show increased flexibility of tail tendons and ligaments such that a knot can be tied in the tailThbs2tm1Bst/Thbs2tm1Bsteither: (involves: 129S4/SvJae * 129X1/SvJ) or (involves: 129X1/SvJ)
Bone and skin abnormalities in Thbs2tm1Bst/Thbs2tm1Bst miceThbs2tm1Bst/Thbs2tm1Bsteither: (involves: 129S4/SvJae * 129X1/SvJ) or (involves: 129X1/SvJ)
Thbs2tm1Bst/Thbs2tm1Bst reticular dermis contains larger collagen fibrils with irregular contoursThbs2tm1Bst/Thbs2tm1Bsteither: (involves: 129S4/SvJae * 129X1/SvJ) or (involves: 129X1/SvJ)
Tendons of the Thbs2tm1Bst/Thbs2tm1Bst mouse contain more large collagen fibrils than wild-typeThbs2tm1Bst/Thbs2tm1Bsteither: (involves: 129S4/SvJae * 129X1/SvJ) or (involves: 129X1/SvJ)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory