Phenotype Images associated with this Allele - MGI

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Phenotype Images associated with this Allele

Nomenclature

Symbol:	Ccl3^tm1Unc
Name:	C-C motif chemokine ligand 3; targeted mutation 1, University of North Carolina
MGI ID:	MGI:1857243
Synonyms:	CCL3^-, MIP-1alpha -, Scya3 -, Scya3^tm1Coo

Images for
Allele

Click images for details

Image	Caption	Genotypes involving this allele
		Allelic Composition	Genetic Background
	Hexb^tm1Rlp/Hexb^tm1Rlp mice exhibit Sandhoff disease phenotypes that are improved in Hexb^tm1Rlp/Hexb^tm1Rlp Ccl3^tm1Unc/Ccl3^tm1Unc mice	Hexb^tm1Rlp/Hexb^tm1Rlp	involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
		Ccl3^tm1Unc/Ccl3^tm1Unc Hexb^tm1Rlp/Hexb^tm1Rlp	involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
	Lessened macrophage/microglia associated pathology in Hexb^tm1Rlp/Hexb^tm1Rlp Ccl3^tm1Unc/Ccl3^tm1Unc mice compared to Hexb^tm1Rlp/Hexb^tm1Rlp mice	Hexb^tm1Rlp/Hexb^tm1Rlp	involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
		Ccl3^tm1Unc/Ccl3^tm1Unc Hexb^tm1Rlp/Hexb^tm1Rlp	involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
	Neuronal apoptosis is reduced in Hexb^tm1Rlp/Hexb^tm1Rlp Ccl3^tm1Unc/Ccl3^tm1Unc mice compared to Hexb^tm1Rlp/Hexb^tm1Rlp mice	Hexb^tm1Rlp/Hexb^tm1Rlp	involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
		Ccl3^tm1Unc/Ccl3^tm1Unc Hexb^tm1Rlp/Hexb^tm1Rlp	involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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