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| Caption | Histology and immunohistochemistry of mouse Tg(Th-MYCN)41Waw/0 tumors. Tumors that arose along the paraverterbral ganglia predominately exhibited (A), a solid cord (B) and molding/pavement morphologies (C) although areas of cells with a ganglion-like appearance were dispersed throughout the tumors (see arrow). The tumors stained homogenously for the neuronal markers- PGP9.5 (D), chromogranin A (E), synaptophsin (F) and neurofilament protein (G). However, only the ganglion-like cells within the tumor stained strongly positive for the neuronal markers - neuron specific enolase (H, I), microtubule associated protein 2 (J, K), Tyrosine Hydroxylase (L). These ganglion-like cells were negative for the proliferation marker Ki67 (M). | ||||
| Copyright | This image is from Teitz T, PLoS One 2011;6(4):e19133, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:172448 | ||||
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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