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| Caption | Ptpn11tm4.2Bgn/Ptpn11+ (LS/+) mice demonstrate phenotypic abnormalities similar to those in human Leopard syndrome. (A) Representative photographs of en face and nose bridge profile (arrow) (image was brightened to enable a clear view of the facial phenotype). (B) Skeletal/chest deformity in heterozygous mutant mice, with pectus carinatum superiorly (arrow) and pectus excavatum inferiorly (arrow). (C) Overall smaller body size in mutant mice as compared with that of wild-type (WT) mice. | ||||
| Copyright | This image is from Marin TM, J Clin Invest 2011 Mar 1;121(3):1026-43 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:172033 | ||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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