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Phenotype Image Detail
Image
Caption Ultrastructural features of contractile and synthetic smooth muscle cells (SMCs) in Mirc32tm1Thbr/Mirc32tm1Thbr mice. (A) Typical contractile SMCs from wild-type animals show numerous focal adhesions (arrows) and intracellular dense bodies (arrowheads). (B) In contrast, synthetic SMCs from mutant mice only rarely display focal adhesions (arrow) and intracellular dense bodies and are rich in rough ER (rER).
Copyright This image is from Boettger T, J Clin Invest 2009 Sep;119(9):2634-47 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:152702
Associated
Alleles
Symbol Name
Mirc32tm1Thbr microRNA cluster 32, including Mir143 and Mir145a; targeted mutation 1, Thomas Braun
Associated
Genotypes
Allelic Composition Genetic Background
Mirc32tm1Thbr/Mirc32tm1Thbr involves: 129/Sv * C57BL/6

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory