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| Caption | Cochlear innervation defects in Slitrk6tm1.1Jaru/Slitrk6tm1.1Jaru (-/-) mice. DiI-traced afferent innervation of apical (A, B) and basal (C, D) turns of the neonatal (P0) cochlea in wild-type (WT) (A, C) and mutant (B, D) mice. Mutant inner ear displays a marked alteration in the spacing of radial fibers in the cochlear innervation (B, D). Innervation defects are distributed evenly throughout the cochlea with no basal-to-apical gradient. DiI-labeled efferent innervation of the cochlear middle turn of WT (E) and mutant (F) neonatal mice. Efferent fibers show abnormalities similar to those noted for the afferent innervation. IGSB, intraganglionic spiral bundle; SG, spiral ganglion. Scale bars, 100 um. | ||||
| Copyright | This image is from Katayama K, PLoS One 2009;4(11):e7786, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:155405 | ||||
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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