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| Caption | Wdfy3tm1a(KOMP)Mbp/Wdfy3tm1a(KOMP)Mbp mice generated through gene targeting exhibit more severe neurodevelopmental defects than Wdfy3disc/Wdfy3disc mice. (a) Nissl stained coronal hemisections through the forebrains of wild-type (WT), heterozygous and homozygous lacZ newborn pups illustrate the malformations present in affected mutants. The yellow dashed line indicates the cortical length in the WT as measured from the corticostriatal boundary to the ventricular apex. The red dashed line indicates differences in cortical length present in the lacZ mutants. (b) Close-ups of cortical segments of lateral and dorsal positions demonstrate cortical thinning in lacZ mutants. | ||||||
| Copyright | This image is from Orosco LA, Nat Commun 2014;5():4692, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:225200 | ||||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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