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| Caption | Homeotic transformation observed in the 4th caudal vertebra of Hotairtm1Vlcg/Hotairtm1Vlcg (Hotair-/-) mice. (A) Visualization of the sacral and caudal region of the mouse skeleton by microCT reveals a homeotic transformation in mutant mice of the 4th caudal vertebra to a structure similar to that of the 3rd caudal vertebra. (B) Dorsal, lateral and ventral comparison of wild-type (WT) and mutant 4th caudal vertebra reveals a structural abnormality in homozygotes indicative of a homeotic transformation. | ||||
| Copyright | This image is from Lai KM, PLoS One 2015;10(4):e0125522, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:233815 | ||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/14/2024 MGI 6.23 |
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