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| Caption | (B) Testes from Kash5tm1b(KOMP)Wtsi/Kash5tm1b(KOMP)Wtsi (Kash5-null) animals are only ~25% of the size of those from wild-type (WT) littermates. (E) Hematoxylin and eosin (H&E) stained testis sections from WT and mutant littermates. The overall structure of the mutant testes is preserved with identifiable, albeit smaller, seminiferous tubules. At higher magnification (center panels) it is apparent that mutant seminiferous tubules lack sperm. WT testes have occasional TUNEL-positive nuclei (bottom panels). In mutant testes, widespread TUNEL staining is seen in ~30% of tubule cross sections. | ||||
| Copyright | This image is from Horn HF, J Cell Biol 2013 Sep 30;202(7):1023-39, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:201813 | ||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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