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Phenotype Image Detail
Image
Caption Gross appearance and skeletal specimens of whole skeleton (B), forelimb (C), lumbar spine (D), ilia (E), and forepaw (F) of wild-type, Col2a1Rgsc856/Col2a1+ (hetero), and Col2a1Rgsc856/Col2a1Rgsc856 (homo) mutant mice at E18.5. The homozygotes exhibited a severe skeletal dysplasia, including extremely shortened limbs, platyspondyly, severe pelvic hypoplasia, and brachydactyly.
Copyright This image is from Furuichi T, Mamm Genome 2011 Jun;22(5-6):318-28 and is displayed with the permission of Springer Science + Business Media, Inc., New York who owns the copyright. J:171906
Associated
Alleles
Symbol Name
Col2a1Rgsc856 collagen, type II, alpha 1; RIKEN Genomic Sciences Center (GSC), 856
Associated
Genotypes
Allelic Composition Genetic Background
Col2a1Rgsc856/Col2a1+ involves: C57BL/6JJcl * DBA/2JJcl
Col2a1Rgsc856/Col2a1Rgsc856 involves: C57BL/6JJcl * DBA/2JJcl

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory