Phenotype Image Detail

Image

Caption

(A-D) Gross views of cardiovascular structures of newborn Eya1^tm1Rilm / Tbx1^tm1Bem compound mutants. Asterisk in C denotes interrupted aortic arches. Ao, aortic artery, BCA, brachiocephalic artery, CA, cervical aortic arch; IAA-B, interrupted aortic arch type B; LCC, left common carotid artery; LSC, left subclavian artery; p, pulmonary artery; PTA, persistent truncus arteriosis; RCC, right common carotid artery; RSC, right subclavian artery; Tr, trachea; VR, vascular ring.

This image is from Guo C, J Clin Invest 2011 Apr 1;121(4):1585-95 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:172023

Associated
Alleles

Symbol	Name
Eya1^tm1Rilm	EYA transcriptional coactivator and phosphatase 1; targeted mutation 1, Richard Maas
Tbx1^tm1Bem	T-box 1; targeted mutation 1, Bernice E Morrow

Associated
Genotypes

Allelic Composition	Genetic Background
Eya1^tm1Rilm/Eya1⁺ Tbx1^tm1Bem/Tbx1⁺	involves: 129 * C57BL/6 * CD-1 * SJL
Eya1^tm1Rilm/Eya1^tm1Rilm Tbx1^tm1Bem/Tbx1⁺	involves: 129 * C57BL/6 * CD-1 * SJL

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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