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Phenotype Image Detail
Image
Caption Disruption of Spg11 in mice results in a severe spastic and ataxic gait disorder. (A-B) Representative single video frame of a wild-type (WT) (A) and Spg11Gt(EUCE0085f05)Hmgu/Spg11Gt(EUCE0085f05)Hmgu (KO) (B) mouse 14 months of age walking on a beam at the moment when the toe of the hind limb is taken off. The foot-base-angle (FBA) is indicated by white lines.
Copyright This image is from Varga RE, PLoS Genet 2015 Aug;11(8):e1005454, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:228803
Associated
Alleles
Symbol Name
Spg11Gt(EUCE0085f05)Hmgu SPG11, spatacsin vesicle trafficking associated; gene trap EUCE0085f05, Helmholtz Zentrum Muenchen GmbH
Associated
Genotypes
Allelic Composition Genetic Background
Spg11Gt(EUCE0085f05)Hmgu/Spg11Gt(EUCE0085f05)Hmgu involves: 129P2/OlaHsd * C57BL/6

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory