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Phenotype Image Detail
Image
Caption Cauda-retrieved spermatozoa of Gpx5tm1115.2Arte/Gpx5tm1115.2Arte (KO) animals suffer oxidative damages. (A) Immunodetection of the nuclear adduct 8-oxodG in cauda epididymidis-retrieved spermatozoa preparations from 6-month-old wild-type (WT), KO, or hydrogen perioxide-treated WT male mice. Images are representative of several distinct detections. (B) Histograms showing the percentage of 8-oxodG-positive spermatozoa in cauda epididymidis-retrieved spermatozoa preparations, from 6-month-old WT, KO, and positive control (WT spermatozoa treated with hydrogen peroxide) male mice. Data are mean SEM. n = 3. **P < 0.05.
Copyright This image is from Chabory E, J Clin Invest 2009 Jul;119(7):2074-85 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:152563
Associated
Alleles
Symbol Name
Gpx5tm1115.2Arte glutathione peroxidase 5; targeted mutation 1115.2, TaconicArtemis
Associated
Genotypes
Allelic Composition Genetic Background
Gpx5tm1115.2Arte/Gpx5tm1115.2Arte involves: C57BL/6 * C57BL/6N

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory