| Image |
|
||||
| Caption | Confocal analysis of sciatic nerve endoneurial matrix in wild-type (WT, +/+) and Vwa1tm1Jfba/Vwa1tm1Jfba (-/-) mice. Immunofluorescent staining for collagen VI is significantly weaker in the mutant mice (B) than in WT (A) mice. Visualization of the field in image B with increased gain (C) reveals that the collagen VI matrix is disorganized as well as reduced in the mutant mouse. Perlecan still forms an intact basement membrane structure in the mutant endoneurium (D). The collagen VI structures in the outer perineurium layer (arrowheads) are unaffected in the mutant (F) compared with the WT (E) mouse. Bar, 10 um. | ||||
| Copyright | This image is from Allen JM, J Biol Chem 2009 May 1;284(18):12020-30 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:149746 | ||||
|
Associated Alleles |
|
||||
|
Associated Genotypes |
|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
|
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 04/23/2024 MGI 6.23 |
|
|
|
||
Analysis Tools