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Phenotype Image Detail
Image
Caption Genetic deletion of Letm1 dramatically reduces mouse embryonic survival. (B) Representative images of wild-type (WT) (left) and Letm1Gt(DD0926)Wtsi/Letm1+ (Letm1+/-) and Letm1Gt(CC0204)Wtsi/Letm1+ (Letm1+/-) mouse embryos. (C) BrdU and TUNEL staining in E9.5 WT and heterozygous mutant mouse embryos indicates decreased BrdU incorporation but no significant apoptosis. (Scale bar, 200 um).
Copyright This image is from Jiang D, Proc Natl Acad Sci U S A 2013 Jun 11;110(24):E2249-54. Copyright 2013 National Academy of Sciences, U.S.A. J:222017
Associated
Alleles
Symbol Name
Letm1Gt(CC0204)Wtsi leucine zipper-EF-hand containing transmembrane protein 1; gene trap CC0204, Wellcome Trust Sanger Institute
Letm1Gt(DD0926)Wtsi leucine zipper-EF-hand containing transmembrane protein 1; gene trap DD0926, Wellcome Trust Sanger Institute
Associated
Genotypes
Allelic Composition Genetic Background
Letm1Gt(DD0926)Wtsi/Letm1+ 129S.129P2-Letm1Gt(DD0926)Wtsi
Letm1Gt(CC0204)Wtsi/Letm1+ 129S.129P2-Letm1Gt(CC0204)Wtsi
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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09/30/2025
MGI 6.24 		The Jackson Laboratory