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Phenotype Image Detail
Image
Caption Morphological defects of Baz1atm1.1Sky/Baz1atm1.1Sky (-/-) sperm. (A) Bright-field images of sperm heads overlaid with DAPI fluorescence (blue). Bar = 2 um. Sperm displayed an array of aberrant head morphologies (teratospermia), all of which lacked a normal hook characteristic of wild-type sperm heads. (B) Bright-field images of sperm. Bar = 5 um. Mutant sperm have numerous tail abnormalities, including frequent narrowing of the annulus (ii and v). Other defects included heads folded back against the tail (iii), two tails (iv), midpieces folded back against the tail (v), and coiling of the tail around the head (vi).
Copyright This image is from Dowdle JA, PLoS Genet 2013 Nov;9(11):e1003945, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:223044
Associated
Alleles
Symbol Name
Baz1atm1.1Sky bromodomain adjacent to zinc finger domain 1A; targeted mutation 1.1, Scott Keeney
Associated
Genotypes
Allelic Composition Genetic Background
Baz1atm1.1Sky/Baz1atm1.1Sky involves: C57BL/6J * FVB/NJ

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory